Evidence map›Paper›PMID 34685161›Full record

ArticleNanomaterials (Basel, Switzerland)2021

Characterization of Gold Nanorods Conjugated with Synthetic Glycopolymers Using an Analytical Approach Based on spICP-SFMS and EAF4-MALS.

Milica Velimirovic, Alessia Pancaro, Robert Mildner, Panagiotis G Georgiou, Kristof Tirez, Inge Nelissen, Christoph Johann, Matthew I Gibson, Frank Vanhaecke

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Milica VelimirovicDepartment of Chemistry, Atomic & Mass Spectrometry-A&MS Research Group, Campus Sterre, Ghent University, Krijgslaan 281-S12, 9000 Ghent, Belgium.ORCID 0000-0002-3233-8837
Alessia PancaroFlemish Institute for Technological Research (VITO), Boeretang 200, 2400 Mol, Belgium.ORCID 0000-0003-4586-3531
Robert MildnerWyatt Technology Europe GmbH, Hochstrasse 12a, 56307 Dernbach, Germany.
Panagiotis G GeorgiouDepartment of Chemistry, University of Warwick, Gibbet Hill Road, Coventry CV4 7AL, UK.ORCID 0000-0001-8968-1057
Kristof TirezFlemish Institute for Technological Research (VITO), Boeretang 200, 2400 Mol, Belgium.
Inge NelissenFlemish Institute for Technological Research (VITO), Boeretang 200, 2400 Mol, Belgium.ORCID 0000-0002-1248-3463
Christoph JohannWyatt Technology Europe GmbH, Hochstrasse 12a, 56307 Dernbach, Germany.
Matthew I GibsonDepartment of Chemistry, University of Warwick, Gibbet Hill Road, Coventry CV4 7AL, UK.ORCID 0000-0002-8297-1278
Frank VanhaeckeDepartment of Chemistry, Atomic & Mass Spectrometry-A&MS Research Group, Campus Sterre, Ghent University, Krijgslaan 281-S12, 9000 Ghent, Belgium.ORCID 0000-0002-1884-3853

Funding

H2020-MSCA-ITN 814236Research Foundation - Flanders 12ZD120N
6 · The paper itself

Abstract

A new comprehensive analytical approach based on single-particle inductively coupled plasma-sector field mass spectrometry (spICP-SFMS) and electrical asymmetric-flow field-flow-fractionation combined with multi-angle light scattering detection (EAF4-MALS) has been examined for the characterization of galactosamine-terminated poly(N-hydroxyethyl acrylamide)-coated gold nanorods (GNRs) in two different degrees of polymerization (DP) by tuning the feed ratio (short: DP 35; long: DP 60). spICP-SFMS provided information on the particle number concentration, size and size distribution of the GNRs, and was found to be useful as an orthogonal method for fast characterization of GNRs. Glycoconjugated GNRs were separated and characterized via EAF4-MALS in terms of their size and charge and compared to the bare GNRs. In contrast to spICP-SFMS, EAF4-MALS was also able of providing an estimate of the thickness of the glycopolymer coating on the GNRs surface.

Indexed as

electrical asymmetric-flow field-flow-fractionation combined with multi-angle light scatteringgold nanorodsgold nanorods conjugated with synthetic glycopolymershigh-resolution single-particle inductively coupled plasma-mass spectrometry

Identifiers

PMID34685161
PMCPMC8539460

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.