Evidence map›Paper›PMID 34685120›Full record

ReviewNanomaterials (Basel, Switzerland)2021

Biosensing Using SERS Active Gold Nanostructures.

Gour Mohan Das, Stefano Managò, Maria Mangini, Anna Chiara De Luca

Open access · goldAbstract readReview
In one paragraph

Review in Nanomaterials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 70 citations in OpenAlex.

  1. Review
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  5. Semiconducting SnORSC advances · 2026
    Article
  6. Metal-Enhanced Fluorescence for the Biologist's Cellular Imaging Toolkit: Design Principles and Recent Applications.BioEssays : news and reviews in molecular, cellular and developmental biology · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Gour Mohan DasLaboratory of Biophotonics and Advanced Microscopy, Second Unit, Institute of Experimental Endocrinology and Oncology "G. Salvatore" (IEOS), National Research Council (CNR), Via P. Castellino 111, 80131 Naples, Italy.ORCID 0000-0002-9308-130X
Stefano ManagòLaboratory of Biophotonics and Advanced Microscopy, Second Unit, Institute of Experimental Endocrinology and Oncology "G. Salvatore" (IEOS), National Research Council (CNR), Via P. Castellino 111, 80131 Naples, Italy.ORCID 0000-0002-7445-385X
Maria ManginiLaboratory of Biophotonics and Advanced Microscopy, Second Unit, Institute of Experimental Endocrinology and Oncology "G. Salvatore" (IEOS), National Research Council (CNR), Via P. Castellino 111, 80131 Naples, Italy.ORCID 0000-0002-4524-6317
Anna Chiara De LucaLaboratory of Biophotonics and Advanced Microscopy, Second Unit, Institute of Experimental Endocrinology and Oncology "G. Salvatore" (IEOS), National Research Council (CNR), Via P. Castellino 111, 80131 Naples, Italy.ORCID 0000-0002-3696-8465
Institute for Experimental Endocrinology and Oncology · IT

Funding

Campania Region POR FESR PROGETTO PLATT 2014/2020Italian Association for Cancer Research 21420Italian Ministry of Health, Ricerca Finalizzata GR-2018-12367517Italian Ministry of Research, PON NeON ARS01_00769
6 · The paper itself

Abstract

Surface-enhanced Raman spectroscopy (SERS) has become a powerful tool for biosensing applications owing to its fingerprint recognition, high sensitivity, multiplex detection, and biocompatibility. This review provides an overview of the most significant aspects of SERS for biomedical and biosensing applications. We first introduced the mechanisms at the basis of the SERS amplifications: electromagnetic and chemical enhancement. We then illustrated several types of substrates and fabrication methods, with a focus on gold-based nanostructures. We further analyzed the relevant factors for the characterization of the SERS sensor performances, including sensitivity, reproducibility, stability, sensor configuration (direct or indirect), and nanotoxicity. Finally, a representative selection of applications in the biomedical field is provided.

Indexed as

biosensinggold nanoparticlesSERS

Identifiers

PMID34685120
PMCPMC8539114
OpenAlexW3207594572

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.