Evidence map›Paper›PMID 34685042›Full record

ArticleNanomaterials (Basel, Switzerland)2021

Rational Constructed Ultra-Small Iron Oxide Nanoprobes Manifesting High Performance for

Xiangyan Wang, Lei Chen, Jianxian Ge, Mohammad Javad Afshari, Lei Yang, Qingqing Miao, Ruixue Duan, Jiabin Cui, Chunyi Liu, Jianfeng Zeng and 2 more

Open access · goldAbstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
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  5. Research progress inExtracellular vesicles and circulating nucleic acids · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Xiangyan WangCollege of Food Science & Technology, Shanghai Ocean University, Shanghai 201306, China.
Lei ChenCenter for Molecular Imaging and Nuclear Medicine, State Key Laboratory of Radiation Medicine and Protection, School for Radiological and Interdisciplinary Sciences (RAD-X), Soochow University, Suzhou 215123, China.ORCID 0000-0003-3016-1625
Jianxian GeCenter for Molecular Imaging and Nuclear Medicine, State Key Laboratory of Radiation Medicine and Protection, School for Radiological and Interdisciplinary Sciences (RAD-X), Soochow University, Suzhou 215123, China.
Mohammad Javad AfshariCenter for Molecular Imaging and Nuclear Medicine, State Key Laboratory of Radiation Medicine and Protection, School for Radiological and Interdisciplinary Sciences (RAD-X), Soochow University, Suzhou 215123, China.
Lei YangCollege of Food Science & Technology, Shanghai Ocean University, Shanghai 201306, China.
Qingqing MiaoCenter for Molecular Imaging and Nuclear Medicine, State Key Laboratory of Radiation Medicine and Protection, School for Radiological and Interdisciplinary Sciences (RAD-X), Soochow University, Suzhou 215123, China.
Ruixue DuanCenter for Molecular Imaging and Nuclear Medicine, State Key Laboratory of Radiation Medicine and Protection, School for Radiological and Interdisciplinary Sciences (RAD-X), Soochow University, Suzhou 215123, China.
Jiabin CuiCenter for Molecular Imaging and Nuclear Medicine, State Key Laboratory of Radiation Medicine and Protection, School for Radiological and Interdisciplinary Sciences (RAD-X), Soochow University, Suzhou 215123, China.ORCID 0000-0003-3047-9852
Chunyi LiuCenter for Molecular Imaging and Nuclear Medicine, State Key Laboratory of Radiation Medicine and Protection, School for Radiological and Interdisciplinary Sciences (RAD-X), Soochow University, Suzhou 215123, China.
Jianfeng ZengCenter for Molecular Imaging and Nuclear Medicine, State Key Laboratory of Radiation Medicine and Protection, School for Radiological and Interdisciplinary Sciences (RAD-X), Soochow University, Suzhou 215123, China.
Jian ZhongCollege of Food Science & Technology, Shanghai Ocean University, Shanghai 201306, China.ORCID 0000-0002-2475-3221
Mingyuan GaoCollege of Food Science & Technology, Shanghai Ocean University, Shanghai 201306, China.
Soochow University · CNShanghai Ocean University · CN

Funding

National Key Research and Development Program of China 2018YFA0208800National Natural Science Foundation of China 81720108024Natural Science Foundation of Jiangsu Province BK20191418Nature Science Foundation of Jiangsu Higher Education Institutions of China 20KJA150006Priority Academic Program Development of Jiangsu Higher Education InstitutionsSuzhou Key Industry Technology Innovation Projects SYG202036
6 · The paper itself

Abstract

Precise diagnosis and monitoring of cancer depend on the development of advanced technologies for in vivo imaging. Owing to the merits of outstanding spatial resolution and excellent soft-tissue contrast, the application of magnetic resonance imaging (MRI) in biomedicine is of great importance. Herein, Angiopep-2 (ANG), which can simultaneously help to cross the blood-brain barrier and target the glioblastoma cells, was rationally combined with the 3.3 nm-sized ultra-small iron oxide (Fe

Indexed as

glioblastomaMRIT1 contrast agentultra-small iron oxide nanoparticles

Identifiers

PMID34685042
PMCPMC8540453
OpenAlexW3204696910

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.