ArticleNanomaterials (Basel, Switzerland)2021
Biofilm-Resistant Nanocoatings Based on ZnO Nanoparticles and Linalool.
Article in Nanomaterials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Targeting ESKAPE pathogens with ZnS and Au@ZnS Core-Shell nanoconjugates for improved biofilm control.Scientific reports · 2025Article
- Antibacterial Properties of PMMA/ZnO(NanoAg) Coatings for Dental Implant Abutments.Materials (Basel, Switzerland) · 2025Article
- Zinc Oxide-Loaded Recycled PET Nanofibers for Applications in Healthcare and Biomedical Devices.Polymers · 2024Article
- Electrophoretic deposition of polyvinyl alcohol, C-H NRs along with moringa on an SS substrate for orthopedic implant applications.RSC advances · 2024Article
- ZnO Nanoparticles Enhance the Antimicrobial Properties of Two-Sided-Coated Cotton Textile.Nanomaterials (Basel, Switzerland) · 2024Article
- Iron-tannic acid nano-coating: A promising treatment approach for enhancingSaudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2024Article
- Nanostructured Coatings Based on Graphene Oxide for the Management of Periprosthetic Infections.International journal of molecular sciences · 2024Article
- Influence of the Alcohols on the ZnO Synthesis and Its Properties: The Photocatalytic and Antimicrobial Activities.Pharmaceutics · 2022Article
- Nanoparticles for Antimicrobial Agents Delivery-An Up-to-Date Review.International journal of molecular sciences · 2022Review
- Metal-Based Nanoparticles: Antibacterial Mechanisms and Biomedical Application.Microorganisms · 2022Review
- Optimization of Technological Parameters of the Process of Forming Therapeutic Biopolymer Nanofilled Films.Nanomaterials (Basel, Switzerland) · 2022Article
- A Review on Current Designation of Metallic Nanocomposite Hydrogel in Biomedical Applications.Nanomaterials (Basel, Switzerland) · 2022Review
- Inorganic Nanoparticles in Bone Healing Applications.Pharmaceutics · 2022Review
Corrections and comments
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Authors and funding
16 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Biofilms represent an increasing challenge in the medical practice worldwide, imposing a serious threat to public health. As bacterial strains have developed antibiotic resistance, researcher's attention has been extensively focused on developing more efficient antimicrobial strategies. In this context, the present study reports the synthesis, physicochemical characterization, ex vivo biodistribution, and in vitro evaluation of the capacity of nanostructured surfaces based on zinc oxide (ZnO) and biologically active molecules to modulate clinically relevant microbial biofilms. ZnO nanoparticles (NPs) were synthesized through a co-precipitation method without thermal treatment. The matrix-assisted pulsed laser evaporation (MAPLE) was applied for preparing nanostructured coatings based on ZnO NPs surface modified with linalool that were further characterized by X-ray diffraction (XRD), thermogravimetric analysis with differential scanning calorimetry (TGA-DSC), scanning electron microscopy (SEM), transmission electron microscopy with selected area electron diffraction (TEM-SAED), Fourier-transform infrared spectroscopy (FT-IR), and infrared microscopy (IRM). Histological analyses carried out at 7 days and 14 days after the intraperitoneal administration of linalool modified ZnO NPs revealed the absence of the latter from the brain, kidney, liver, lung, myocardium, and pancreas. Through in vitro assays on prokaryotic cells, it was proven that ZnO coatings hinder microbial biofilm formation of both Gram-positive and Gram-negative bacteria strains.
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