Evidence map›Paper›PMID 34684953›Full record

ArticleNanomaterials (Basel, Switzerland)2021

Preparation and Characterization of Anti-Cancer Crystal Drugs Based on Erythrocyte Membrane Nanoplatform.

Lili Ren, Lirong Qiu, Binbin Huang, Jun Yin, Yaning Li, Xiaolong Yang, Guoguang Chen

Open access · goldAbstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 12 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 2 countries.

Lili RenSchool of Pharmacy, Nanjing Tech University, 5th Mofan Road, Nanjing 210094, China.ORCID 0000-0001-6423-9625
Lirong QiuSchool of Pharmacy, Nanjing Tech University, 5th Mofan Road, Nanjing 210094, China.
Binbin HuangSchool of Pharmacy, Nanjing Tech University, 5th Mofan Road, Nanjing 210094, China.
Jun YinSchool of Pharmacy, Nanjing Tech University, 5th Mofan Road, Nanjing 210094, China.
Yaning LiSchool of Pharmacy, Nanjing Tech University, 5th Mofan Road, Nanjing 210094, China.
Xiaolong YangSchool of Pharmacy, Nanjing Tech University, 5th Mofan Road, Nanjing 210094, China.ORCID 0000-0002-3328-7066
Guoguang ChenSchool of Pharmacy, Nanjing Tech University, 5th Mofan Road, Nanjing 210094, China.
Nanjing Tech University · CN

Funding

Science and Technology Planning Project of Jiangsu Province of China. Joint scientific research project of Sino-foreign cooperation platform in NJTECH university. The Jiangsu Synergetic Innovation Center for Advanced Bio-Manufacture. BE2019738
6 · The paper itself

Abstract

The simple and functional modification of the nanoparticle's surface is used to efficiently deliver chemotherapeutic drugs for anti-cancer treatment. Here, we construct a nanocrystalline drug delivery system with doxorubicin wrapped in red blood cell membranes for the treatment of mouse breast cancer models. Compared with traditional free drug treatments, the biodegradable natural red blood cell membrane is combined with pure crystalline drugs. The nanoparticles obtained by the preparation method have superior properties, such as good stability, significantly delaying the release of drugs and enhancing the inhibitory effect on tumor cells. This study shows that the design of RBC as an outsourced drug delivery system provides a promising foundation for the continued development, clinical trials, and nanomedicine research of anti-cancer drug nanocarriers in the future.

Indexed as

antitumor effectdrug deliveryerythrocyte membranenanocrystals

Identifiers

PMID34684953
PMCPMC8540031
OpenAlexW3203175303

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.