Evidence map›Paper›PMID 34684886›Full record

ArticleMolecules (Basel, Switzerland)2021

Effect of the Amount of Polysorbate 80 and Oregano Essential Oil on the Emulsion Stability and Characterization Properties of Sodium Alginate Microcapsules.

Juste Baranauskaite, Mehmet Ali Ockun, Burcu Uner, Cetin Tas, Liudas Ivanauskas

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Juste BaranauskaiteDepartment of Pharmaceutical Technology, Faculty of Pharmacy, Yeditepe University, Kayisdagi Cd., Atasehir, Istanbul 34755, Turkey.ORCID 0000-0002-0358-5759
Mehmet Ali OckunDepartment of Pharmacognosy, Faculty of Pharmacy, Yeditepe University, Kayisdagi Cd., Atasehir, Istanbul 34755, Turkey.
Burcu UnerDepartment of Pharmaceutical Technology, Faculty of Pharmacy, Yeditepe University, Kayisdagi Cd., Atasehir, Istanbul 34755, Turkey.ORCID 0000-0003-4691-0432
Cetin TasDepartment of Pharmaceutical Technology, Faculty of Pharmacy, Yeditepe University, Kayisdagi Cd., Atasehir, Istanbul 34755, Turkey.
Liudas IvanauskasDepartment of Analytical and Toxicological Chemistry, Faculty of Pharmacy, Medical Academy, Lithuanian University of Health Sciences, 13 Sukileliu Str., LT-50161 Kaunas, Lithuania.ORCID 0000-0001-5390-2161
Yeditepe University · TRLithuanian University of Health Sciences · LT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Essential oils have a high volatility that leads to evaporation and loss of their pharmacological effect when exposed to the environment. The objectives of the present work were to prepare microcapsules with oregano essential oil by extrusion using sodium alginate as a shell material and non-ionic surfactant polysorbate 80 as an emulsifier to stabilize the emulsion. The present study was aimed to evaluate the physical parameters of microcapsules and to compare the influence of the amount of emulsifier and the essential oil-to-emulsifier ratio on the capsules' physical parameters and encapsulation efficiency; to our knowledge, the existing research had not yet revealed whether unstable emulsion affects the encapsulation efficiency of oregano essential oil. This study showed that increasing the emulsifier amount in the formulation significantly influenced encapsulation efficiency and particle size. Moreover, increasing the emulsion stability positively influenced the encapsulation efficiency. The emulsion creaming index depended on the emulsifier amount in the formulation: the highest creaming index (%) was obtained with the highest amount of polysorbate 80. However, the essential oil-to-polysorbate 80 ratio and essential oil amount did not affect the hardness of the microcapsules (

Indexed as

AlginatesCapsulesEmulsifying AgentsEmulsionsOils, VolatileOriganumParticle SizePolysorbatesAlginatesCapsulesEmulsifying AgentsEmulsionsOils, VolatilePolysorbatescarvacrolextrusionGC/MSHPTLC

Identifiers

PMID34684886
PMCPMC8538521
OpenAlexW3205753888

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.