ReviewMolecules (Basel, Switzerland)2021
Choline Chloride-Based DES as Solvents/Catalysts/Chemical Donors in Pharmaceutical Synthesis.
Review in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Challenging the Surface Area Paradigm: A Critical Review of Low-BET Metal-Organic Frameworks for the Adsorption of Organic Water Pollutants.Nanomaterials (Basel, Switzerland) · 2026Review
- Natural deep eutectic solvents as plasticizers for advancing sustainable strain sensors.RSC advances · 2026Article
- Azelaic acid-integrated therapeutic deep eutectic systems: overcoming solubility and permeability barriers for enhanced transdermal drug delivery.RSC advances · 2026Article
- Article
- Sustainable Extraction ofInternational journal of molecular sciences · 2026Article
- Cellulose microfiber production from green seaweed Ulva lactuca using hydrated deep eutectic solvent.Biotechnology letters · 2026Article
- Article
- Deep Eutectic Solvents in Polymeric Drug Carriers: Insights into Release Behavior and Functional Integration.ChemistryOpen · 2025Review
- Natural deep eutectic solvents (NaDES): green solvents for pharmaceutical applications and beyond.Green chemistry : an international journal and green chemistry resource : GC · 2025Review
- Study of fluconazole drug behavior in deep eutectic solvents: thermodynamic properties, solubility measurement, and fluorescence spectroscopy.RSC advances · 2025Article
- The Role of Natural Deep Eutectic Solvents in a Hydrogel Formulation Containing Lidocaine.Pharmaceutics · 2025Article
- Designed Reactive Natural Deep Eutectic Solvents for Lipase-Catalyzed Esterification.Molecules (Basel, Switzerland) · 2025Article
- Article
- Exploring Deep Eutectic Solvents as Pharmaceutical Excipients: Enhancing the Solubility of Ibuprofen and Mefenamic Acid.Pharmaceuticals (Basel, Switzerland) · 2024Article
- Preparation and Characterization of Natural Deep Eutectic Solvents (NADESs): Application in the Extraction of Phenolic Compounds from Araza Pulp (Foods (Basel, Switzerland) · 2024Article
- Deep Eutectic Liquids as a Topical Vehicle for Tadalafil: Characterisation and Potential Wound Healing and Antimicrobial Activity.Molecules (Basel, Switzerland) · 2023Article
- The Role of Water Content of Deep Eutectic Solvent Ethaline in the Anodic Process of Gold Electrode.Molecules (Basel, Switzerland) · 2023Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
DES are mixtures of two or more compounds, able to form liquids upon mixing, with lower freezing points when compared to the individual constituents (eutectic mixtures). This attitude is due to the specific hydrogen-bond interactions network between the components of the mixture. A notable characteristic of DES is the possibility to develop tailor-made mixtures by changing the components ratios or a limited water dilution, for special applications, making them attractive for pharmaceutical purposes. In this review, we focused our attention on application of ChCl-based DES in the synthesis of pharmaceutical compounds. In this context, these eutectic mixtures can be used as solvents, solvents/catalysts, or as chemical donors and we explored some representative examples in recent literature of such applications.
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Registered trials
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