Evidence map›Paper›PMID 34684834›Full record

ArticleMolecules (Basel, Switzerland)2021

Palmatine, a Bioactive Protoberberine Alkaloid Isolated from

Aneta Grabarska, Paula Wróblewska-Łuczka, Wirginia Kukula-Koch, Jarogniew J Łuszczki, Eleftherios Kalpoutzakis, Grzegorz Adamczuk, Alexios Leandros Skaltsounis, Andrzej Stepulak

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
7.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 50 citations in OpenAlex.

  1. Article
  2. Review
  3. Exploration and Preliminary Investigation of WiledCurrent issues in molecular biology · 2026
    Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. Review
  10. Isolation and Quantification of Palmatine fromDrug design, development and therapy · 2024
    Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Isoquinoline Alkaloids fromInternational journal of molecular sciences · 2022
    Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Aneta GrabarskaDepartment of Biochemistry and Molecular Biology, Medical University of Lublin, Chodzki 1, 20-093 Lublin, Poland.ORCID 0000-0002-3823-1467
Paula Wróblewska-ŁuczkaDepartment of Pathophysiology, Medical University of Lublin, Jaczewskiego 8b, 20-090 Lublin, Poland.ORCID 0000-0002-7099-1968
Wirginia Kukula-KochDepartment of Pharmacognosy with Medicinal Plants Garden, Medical University of Lublin, Chodzki 1, 20-093 Lublin, Poland.ORCID 0000-0001-7076-600X
Jarogniew J ŁuszczkiDepartment of Pathophysiology, Medical University of Lublin, Jaczewskiego 8b, 20-090 Lublin, Poland.ORCID 0000-0002-3059-0393
Eleftherios KalpoutzakisLaboratory of Pharmacognosy and Natural Products Chemistry, School of Pharmacy, National and Kapodistrian University of Athens, Panepistimioupoli Zografou, 15771 Athens, Greece.
Grzegorz AdamczukIndependent Medical Biology Unit, Medical University of Lublin, Jaczewskiego 8b, 20-090 Lublin, Poland.ORCID 0000-0003-1677-7247
Alexios Leandros SkaltsounisLaboratory of Pharmacognosy and Natural Products Chemistry, School of Pharmacy, National and Kapodistrian University of Athens, Panepistimioupoli Zografou, 15771 Athens, Greece.
Andrzej StepulakDepartment of Biochemistry and Molecular Biology, Medical University of Lublin, Chodzki 1, 20-093 Lublin, Poland.
Medical University of Lublin · PLNational and Kapodistrian University of Athens · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Palmatine (PLT) is a natural isoquinoline alkaloid that belongs to the class of protoberberines and exhibits a wide spectrum of pharmacological and biological properties, including anti-cancer activity. The aim of our study was to isolate PLT from the roots of

Indexed as

Antineoplastic Agents, PhytogenicAntineoplastic Combined Chemotherapy ProtocolsApoptosisBerberine AlkaloidsBerberisBreast NeoplasmsCell Line, TumorCell ProliferationCell SurvivalDoxorubicinDrug SynergismFemaleHumansMCF-7 CellsPhytotherapyPlant RootsAntineoplastic Agents, PhytogenicBerberine AlkaloidsDoxorubicinpalmatineprotoberberineReceptors, EstrogenBerberidaceaeBerberis creticabreast cancerHPLC-MSisobolographic analysisisoquinoline alkaloidsnatural productspalmatine

Identifiers

PMID34684834
PMCPMC8538708
OpenAlexW3205227314

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.