Evidence map›Paper›PMID 34684829›Full record

ArticleMolecules (Basel, Switzerland)2021

The Unexplored Wound Healing Activity of

Athanasia I Kasouni, Theodoros G Chatzimitakos, Constantine D Stalikas, Theoni Trangas, Alexandra Papoudou-Bai, Anastassios N Troganis

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
6.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

  1. A critical overview of challenging roles of medicinal plants in improvement of wound healing technology.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2024
    Pooled it
  2. Article
  3. Review
  4. GC-MS/MS Analysis and Wound Repair Potential ofCurrent pharmaceutical biotechnology · 2025
    Article
  5. Phytochemical analysis ofOpen life sciences · 2025
    Article
  6. Article
  7. International journal of molecular sciences · 2024
    Review
  8. Article
  9. Article
  10. Article
  11. Protective Effect ofLife (Basel, Switzerland) · 2023
    Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Athanasia I KasouniLaboratory of Biophysical Chemistry, Department of Biological Applications and Technologies, University of Ioannina, 45110 Ioannina, Greece.
Theodoros G ChatzimitakosLaboratory of Analytical Chemistry, Department of Chemistry, University of Ioannina, 45110 Ioannina, Greece.ORCID 0000-0001-8885-2483
Constantine D StalikasLaboratory of Analytical Chemistry, Department of Chemistry, University of Ioannina, 45110 Ioannina, Greece.ORCID 0000-0002-6189-0006
Theoni TrangasLaboratory of Biochemistry, Department of Biological Applications and Technologies, University of Ioannina, 45110 Ioannina, Greece.
Alexandra Papoudou-BaiDepartment of Pathology, Faculty of Medicine, School of Health Sciences, University of Ioannina, 45110 Ioannina, Greece.ORCID 0000-0002-3932-6652
Anastassios N TroganisLaboratory of Biophysical Chemistry, Department of Biological Applications and Technologies, University of Ioannina, 45110 Ioannina, Greece.ORCID 0000-0002-7794-542X
University of Ioannina · GR

Funding

General Secretariat for Research and Technology 1230HELLENIC FOUNDATION FOR RESEARCH AND INNOVATION (HFRI) 1230
6 · The paper itself

Abstract

Wound healing is a great challenge in many health conditions, especially in non-healing conditions. The search for new wound healing agents continues unabated, as the use of growth factors is accompanied by several limitations. Medicinal plants have been used for a long time in would healing, despite the lack of scientific evidence veryfying their efficacy. Up to now, the number of reports about medicinal plants with wound healing properties is limited.

Indexed as

AnimalsAnti-Inflammatory AgentsAntioxidantsCell CycleCell LineCell MovementCell ProliferationHEK293 CellsHumansMalePlant ExtractsPlants, MedicinalRatsRats, WistarSkinUrtica dioicaAnti-Inflammatory AgentsAntioxidantsPlant Extractsanti-inflammatorycell cycle progressioncell proliferation and migrationhistopathological studyUrtica dioica L.wound healing

Identifiers

PMID34684829
PMCPMC8540079
OpenAlexW3206099922

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.