Construction of a Tandem Repeat Peptide Sequence with Pepsin Cutting Sites to Produce Recombinant α-Melanocyte-Stimulating Hormone.

Dai-Lin Jiang, Chao-Ling Yao, Nien-Jen Hu, Yung-Chuan Liu

Open access · goldAbstract read

In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it

0cells of the map it votes in

2citing papers in PubMed

0.1field-weighted citation impact, top 49% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

The effect of monomers number in peptides on Escherichia coli strain productivity and inclusion bodies-associated target protein accumulation.Folia microbiologica · 2026
Article
A Lambda-evo (λApplied microbiology and biotechnology · 2025
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Dai-Lin JiangDepartment of Chemical Engineering, National Chung Hsing University, Taichung 402, Taiwan.

Chao-Ling YaoDepartment of Chemical Engineering, National Cheng Kung University, Tainan 701, Taiwan.ORCID 0000-0002-7196-5833

Nien-Jen HuGraduate Institute of Biochemistry, National Chung Hsing University, Taichung 402, Taiwan.ORCID 0000-0002-0917-0677

Yung-Chuan LiuDepartment of Chemical Engineering, National Chung Hsing University, Taichung 402, Taiwan.ORCID 0000-0002-4800-3337

National Chung Hsing University · TWNational Cheng Kung University · TW

Funding

Ministry of Science and Technology (MOST), Taiwan Grants numbers 109-2221-E-005 -028 -MY2Ministry of Science and Technology (MOST), Taiwan Grants numbers 110-2311-B-005 -005 -MY3

6 · The paper itself

Abstract

The production of α-melanocyte-stimulating hormone (α-MSH), a peptide hormone composed of 13 amino acids, is attempted by recombinant expression using

Indexed as

alpha-MSHAmino Acid SequenceAnimalsAntimicrobial Cationic PeptidesCell Line, TumorEscherichia coliGenes, SyntheticMelaninsMelanoma, ExperimentalMicePepsin ARecombinant Fusion ProteinsSpectrometry, Mass, Matrix-Assisted Laser Desorption-IonizationTandem Mass SpectrometryTandem Repeat Sequencesalpha-MSHAntimicrobial Cationic PeptidesMelaninsPepsin ARecombinant Fusion Proteinsantimicrobial peptidepepsin cleavagerecombinant expressiontandem repeat peptidesα-melanocyte-stimulating hormone

Identifiers

PMID34684787

DOI10.3390/molecules26206207

PMCPMC8541268

OpenAlexW3206358228

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.