Evidence map›Paper›PMID 34684779›Full record

ArticleMolecules (Basel, Switzerland)2021

Reconstitution of Caveolin-1 into Artificial Lipid Membrane: Characterization by Transmission Electron Microscopy and Solid-State Nuclear Magnetic Resonance.

Yanli Zhang, Xinyan Zhang, Wenru Kong, Shuqi Wang

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Current Perspectives on Synthetic Compartments for Biomedical Applications.International journal of molecular sciences · 2022
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Yanli ZhangDepartment of Pharmacy, Qilu Hospital of Shandong University, Cheeloo College of Medicine, Jinan 250012, China.
Xinyan ZhangDepartment of Pharmaceutical Sciences, University of Nebraska Medical Center, Omaha, NE 68198, USA.
Wenru KongSchool of Pharmaceutical Sciences, Shandong University, Jinan 250012, China.
Shuqi WangSchool of Pharmaceutical Sciences, Shandong University, Jinan 250012, China.ORCID 0000-0002-5764-8161
Shandong University · CNQilu Hospital of Shandong University · CNUniversity of Nebraska Medical Center · US

Funding

Key Research and Development Project of Shandong Province; the Young Scholars Program of Shandong University; China Scholarship Council 2017GSF218049; 2018WLJH93
6 · The paper itself

Abstract

Caveolin-1 (CAV1), a membrane protein that is necessary for the formation and maintenance of caveolae, is a promising drug target for the therapy of various diseases, such as cancer, diabetes, and liver fibrosis. The biology and pathology of caveolae have been widely investigated; however, very little information about the structural features of full-length CAV1 is available, as well as its biophysical role in reshaping the cellular membrane. Here, we established a method, with high reliability and reproducibility, for the expression and purification of CAV1. Amyloid-like properties of CAV1 and its

Indexed as

Amino Acid SequenceCaveolin 1HumansMagnetic Resonance SpectroscopyMembrane LipidsMembranes, ArtificialMicroscopy, Electron, TransmissionProtein Conformation, alpha-HelicalProtein Conformation, beta-StrandProtein Structure, QuaternaryRecombinant ProteinsCaveolin 1Membrane LipidsMembranes, ArtificialRecombinant Proteinscaveolin-1caveolin scaffolding domainlipid membranesmembrane curvaturessNMRα-helical

Identifiers

PMID34684779
PMCPMC8539922
OpenAlexW3207429062

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.