Evidence map›Paper›PMID 34684743›Full record

ArticleMolecules (Basel, Switzerland)2021

In Silico Identification of Possible Inhibitors for Protein Kinase B (PknB) of

Tatiana F Vieira, Fábio G Martins, Joel P Moreira, Tiago Barbosa, Sérgio F Sousa

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Drug Repurposing TargetingAntibiotics (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Tatiana F VieiraAssociate Laboratory i4HB-Institute for Health and Bioeconomy, Faculdade de Medicina, Universidade do Porto, 4200-319 Porto, Portugal.ORCID 0000-0001-5137-0798
Fábio G MartinsAssociate Laboratory i4HB-Institute for Health and Bioeconomy, Faculdade de Medicina, Universidade do Porto, 4200-319 Porto, Portugal.ORCID 0000-0001-6257-8885
Joel P MoreiraAssociate Laboratory i4HB-Institute for Health and Bioeconomy, Faculdade de Medicina, Universidade do Porto, 4200-319 Porto, Portugal.
Tiago BarbosaAssociate Laboratory i4HB-Institute for Health and Bioeconomy, Faculdade de Medicina, Universidade do Porto, 4200-319 Porto, Portugal.
Sérgio F SousaAssociate Laboratory i4HB-Institute for Health and Bioeconomy, Faculdade de Medicina, Universidade do Porto, 4200-319 Porto, Portugal.ORCID 0000-0002-6560-5284
Universidade do Porto · PT

Funding

Fundação para a Ciência e Tecnologia SFRH/BD/137844/2018, UIDP/04378/2020, UIDB/04378/2020 and 2020.01423.CEECIND/CP1596/CT0003
6 · The paper itself

Abstract

With tuberculosis still being one of leading causes of death in the world and the emergence of drug-resistant strains of

Indexed as

Bacterial ProteinsComputational BiologyComputer SimulationDrug Evaluation, PreclinicalLigandsMolecular Docking SimulationMolecular Dynamics SimulationMycobacterium tuberculosisPhosphorylationProtein Kinase InhibitorsProto-Oncogene Proteins c-aktSignal TransductionTuberculosisBacterial ProteinsLigandsProtein Kinase InhibitorsProto-Oncogene Proteins c-aktMM/GBSAmolecular dockingmolecular dynamics simulationsMycobacterium tuberculosisPknBserine/threonine protein kinasesvirtual screening

Identifiers

PMID34684743
PMCPMC8541300
OpenAlexW3207896111

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.