Evidence map›Paper›PMID 34684733›Full record

ArticleMolecules (Basel, Switzerland)2021

Phenolic Profile, Antioxidant Capacity and Antimicrobial Activity of Nettle Leaves Extracts Obtained by Advanced Extraction Techniques.

Ivona Elez Garofulić, Valentina Malin, Maja Repajić, Zoran Zorić, Sandra Pedisić, Meta Sterniša, Sonja Smole Možina, Verica Dragović-Uzelac

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
10.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 47 citations in OpenAlex.

  1. Antioxidants (Basel, Switzerland) · 2026
    Review
  2. Article
  3. Article
  4. Natural Antimicrobial Activity of Nettle (Food science & nutrition · 2026
    Article
  5. Bacteriostatic Effect of Some Plant Extracts Against Crown Gall Caused byInternational journal of molecular sciences · 2026
    Article
  6. Nettle (Food chemistry: X · 2025
    Article
  7. Article
  8. Article
  9. Food science and biotechnology · 2024
    Review
  10. Article
  11. Article
  12. International journal of molecular sciences · 2024
    Review
  13. Chemical Constituents of Stinging Nettle (International journal of molecular sciences · 2024
    Review
  14. Article
  15. Article
  16. Article
  17. The biological function ofFrontiers in veterinary science · 2024
    Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Ivona Elez GarofulićFaculty of Food Technology and Biotechnology, University of Zagreb, 10000 Zagreb, Croatia.
Valentina MalinBiotechnical Faculty, University of Ljubljana, 1000 Ljubljana, Slovenia.
Maja RepajićFaculty of Food Technology and Biotechnology, University of Zagreb, 10000 Zagreb, Croatia.ORCID 0000-0001-8413-5575
Zoran ZorićFaculty of Food Technology and Biotechnology, University of Zagreb, 10000 Zagreb, Croatia.
Sandra PedisićFaculty of Food Technology and Biotechnology, University of Zagreb, 10000 Zagreb, Croatia.
Meta SternišaBiotechnical Faculty, University of Ljubljana, 1000 Ljubljana, Slovenia.ORCID 0000-0002-2414-3618
Sonja Smole MožinaBiotechnical Faculty, University of Ljubljana, 1000 Ljubljana, Slovenia.ORCID 0000-0001-7949-8128
Verica Dragović-UzelacFaculty of Food Technology and Biotechnology, University of Zagreb, 10000 Zagreb, Croatia.ORCID 0000-0002-4179-3727
University of Zagreb · HRUniversity of Ljubljana · SI

Funding

CEEPUS network CIII-HR-0306-12-1920-M-140167Croatian Science Foundation IP-01-2018-4924Slovenian Research Agency P4-0116
6 · The paper itself

Abstract

Nettle is a widely known plant whose high biological activity and beneficial medicinal effects are attributed to various bioactive compounds, among which polyphenols play an important role. In order to isolate polyphenols and preserve their properties, advanced extraction techniques have been applied to overcome the drawbacks of conventional ones. Therefore, microwave-assisted extraction (MAE) has been optimized for the isolation of nettle leaves polyphenols and it was compared to pressurized liquid extraction (PLE) and conventional heat-reflux extraction (CE). The obtained extracts were analyzed for their individual phenolic profile by UPLC MS

Indexed as

Anti-Bacterial AgentsAnti-Infective AgentsAntioxidantsChromatography, High Pressure LiquidFlavonoidsMicrowavesPhenolsPlant ExtractsPlant LeavesUrtica dioicaAnti-Bacterial AgentsAnti-Infective AgentsAntioxidantsFlavonoidsPhenolsPlant Extractsadvanced extraction techniquesantimicrobial activityantioxidant capacitymicrowave-assisted extractionnettle leavesORACplant polyphenolspressurized liquid extractionUPLC MS2

Identifiers

PMID34684733
PMCPMC8538125
OpenAlexW3205910820

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.