Evidence map›Paper›PMID 34684730›Full record

ArticleMolecules (Basel, Switzerland)2021

Antioxidant Activity and Anti-Apoptotic Effect of the Small Molecule Procyanidin B1 in Early Mouse Embryonic Development Produced by Somatic Cell Nuclear Transfer.

Wei Gao, Tingting Yu, Guomeng Li, Wei Shu, Yongxun Jin, Mingjun Zhang, Xianfeng Yu

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 19 citations in OpenAlex.

  1. Trial
  2. Article
  3. Procyanidin-B1-EnrichedAnimals : an open access journal from MDPI · 2025
    Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Wei GaoJilin Provincial Key Laboratory of Animal Model, College of Animal Science, Jilin University, Changchun 130062, China.
Tingting YuGroup of Non-Human Primates of Reproductive and Stem Cell, Kunming Institute of Zoology, CAS, Kunming 650203, China.
Guomeng LiGroup of Non-Human Primates of Reproductive and Stem Cell, Kunming Institute of Zoology, CAS, Kunming 650203, China.
Wei ShuGroup of Non-Human Primates of Reproductive and Stem Cell, Kunming Institute of Zoology, CAS, Kunming 650203, China.
Yongxun JinJilin Provincial Key Laboratory of Animal Model, College of Animal Science, Jilin University, Changchun 130062, China.
Mingjun ZhangJilin Provincial Key Laboratory of Animal Model, College of Animal Science, Jilin University, Changchun 130062, China.
Xianfeng YuJilin Provincial Key Laboratory of Animal Model, College of Animal Science, Jilin University, Changchun 130062, China.ORCID 0000-0003-0589-2178
Kunming Institute of Zoology · CNJilin University · CN

Funding

Fundamental Research Funds for the Central Universities 45119031C101Jilin Province Science and Technology Development Project 20180623023TC
6 · The paper itself

Abstract

As an antioxidant, procyanidin B1(PB1) can improve the development of somatic cell nuclear transfer (SCNT) embryos; PB1 reduces the level of oxidative stress (OS) during the in vitro development of SCNT embryos by decreasing the level of reactive oxygen species (ROS) and increasing the level of glutathione (GSH) and mitochondrial membrane potential (MMP). Metabolite hydrogen peroxide (H

Indexed as

AnimalsAntioxidantsApoptosisBiflavonoidsCatalaseCatechinChinaEmbryonic DevelopmentFemaleHydrogen PeroxideMembrane Potential, MitochondrialMiceMice, Inbred C57BLMice, Inbred DBANuclear Transfer TechniquesOocytesAntioxidantsBiflavonoidsCatalaseCatechinHydrogen PeroxideProanthocyanidinsprocyanidin B1Reactive Oxygen Speciesembryomouseprocyanidin B1reactive oxygen speciesSCNT

Identifiers

PMID34684730
PMCPMC8540974
OpenAlexW3207232293

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.