Evidence map›Paper›PMID 34684673›Full record

ArticleMolecules (Basel, Switzerland)2021

Synthesis of Halogenated 1,5-Diarylimidazoles and Their Inhibitory Effects on LPS-Induced PGE

Zunhua Yang, Yuanying Fang, Jae-Min Kim, Kyung-Tae Lee, Haeil Park

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 57% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Zunhua YangCollege of Pharmacy, Jiangxi University of Traditional Chinese Medicine, Nanchang 330004, China.
Yuanying FangCollege of Pharmacy, Jiangxi University of Traditional Chinese Medicine, Nanchang 330004, China.
Jae-Min KimCollege of Pharmacy, Kyung Hee University, Seoul 02453, Korea.
Kyung-Tae LeeCollege of Pharmacy, Kyung Hee University, Seoul 02453, Korea.ORCID 0000-0002-3141-3727
Haeil ParkCollege of Pharmacy, Kangwon National University, Chuncheon 24341, Korea.
Jiangxi University of Traditional Chinese Medicine · CNKyung Hee University · KRKangwon National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A series of halogenated 1,5-diarylimidazole compounds were synthesized and their inhibitory effects on LPS-induced PGE

Indexed as

ImidazolesAnimalsAnti-Inflammatory Agents, Non-SteroidalDinoprostoneHalogenationMiceMolecular StructureRAW 264.7 CellsStructure-Activity RelationshipAnti-Inflammatory Agents, Non-SteroidalDinoprostoneimidazoleImidazoles1,5-diarylimidazoleanti-inflammatoryCOX-2halogenationPGE2 production

Identifiers

PMID34684673
PMCPMC8538130
OpenAlexW3206873321

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.