Evidence map›Paper›PMID 34684661›Full record

Trial reportNutrients2021

The Effects of Specific Omega-3 and Omega-6 Polyunsaturated Fatty Acids and Antioxidant Vitamins on Gait and Functional Capacity Parameters in Patients with Relapsing-Remitting Multiple Sclerosis.

Panayiotis Aristotelous, Manos Stefanakis, Marios Pantzaris, Constantinos S Pattichis, Philip C Calder, Ioannis S Patrikios, Giorgos K Sakkas, Christoforos D Giannaki

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 3 countries.

Panayiotis AristotelousDepartment of Life and Health Sciences, University of Nicosia, Nicosia 2417, Cyprus.ORCID 0000-0002-1280-6058
Manos StefanakisDepartment of Life and Health Sciences, University of Nicosia, Nicosia 2417, Cyprus.
Marios PantzarisThe Cyprus Institute of Neurology and Genetics, Nicosia 2371, Cyprus.ORCID 0000-0003-2937-384X
Constantinos S PattichisDepartment of Computer Sciences, University of Cyprus, Nicosia 2109, Cyprus.ORCID 0000-0003-1271-8151
Philip C CalderFaculty of Medicine, University of Southampton, Southampton SO16 6YD, UK.ORCID 0000-0002-6038-710X
Ioannis S PatrikiosSchool of Medicine, European University Cyprus, Nicosia 2404, Cyprus.
Giorgos K SakkasDepartment of PE and Sport Science, University of Thessaly, 42100 Trikala, Greece.ORCID 0000-0002-2462-995X
Christoforos D GiannakiDepartment of Life and Health Sciences, University of Nicosia, Nicosia 2417, Cyprus.ORCID 0000-0003-0029-1189
University of Nicosia · CYEuropean University Cyprus · CYCyprus Institute of Neurology and Genetics · CYUniversity of Cyprus · CYUniversity of Thessaly · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients with multiple sclerosis (MS) are characterized by, among other symptoms, impaired functional capacity and walking difficulties. Polyunsaturated fatty acids (PUFAs) have been found to improve MS patients' clinical outcomes; however, their effect on other parameters associated with daily living activities need further investigation. The current study aimed to examine the effect of a 24-month supplementation with a cocktail dietary supplement formula, the Neuroaspis

Indexed as

AdultAntioxidantsBody CompositionFatty Acids, Omega-3Fatty Acids, Omega-6FemaleGaitHand StrengthHumansKneeMaleMultiple Sclerosis, Relapsing-RemittingTime FactorsVitaminsAntioxidantsFatty Acids, Omega-3Fatty Acids, Omega-6Vitaminsfunctional capacitygaitNeuroaspisTM plp10PUFArelapsing remitting multiple sclerosis

Identifiers

PMID34684661
PMCPMC8540949
OpenAlexW3207919029

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.