Evidence map›Paper›PMID 34684646›Full record

ReviewNutrients2021

Nutraceuticals for Peripheral Vestibular Pathology: Properties, Usefulness, Future Perspectives and Medico-Legal Aspects.

Giuseppe Chiarella, Gianmarco Marcianò, Pasquale Viola, Caterina Palleria, Davide Pisani, Vincenzo Rania, Alessandro Casarella, Alessia Astorina, Alfonso Scarpa, Massimiliano Esposito and 8 more

Open access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Applications and Current Medico-Legal Challenges of Telemedicine in Ophthalmology.International journal of environmental research and public health · 2022
    Review
  8. Review
  9. Drug-Drug Interactions in Vestibular Diseases, Clinical Problems, and Medico-Legal Implications.International journal of environmental research and public health · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 6 institutions in 1 country.

Giuseppe ChiarellaUnit of Audiology, Department of Experimental and Clinical Medicine, Regional Centre of Cochlear Implants and ENT Diseases, Magna Graecia University, 88100 Catanzaro, Italy.ORCID 0000-0002-9829-2229
Gianmarco MarcianòOperative Unit of Pharmacology and Pharmacovigilance, "Mater Domini" Hospital, Department of Health Science, University Magna Graecia, 88100 Catanzaro, Italy.
Pasquale ViolaUnit of Audiology, Department of Experimental and Clinical Medicine, Regional Centre of Cochlear Implants and ENT Diseases, Magna Graecia University, 88100 Catanzaro, Italy.ORCID 0000-0002-2352-1146
Caterina PalleriaOperative Unit of Pharmacology and Pharmacovigilance, "Mater Domini" Hospital, Department of Health Science, University Magna Graecia, 88100 Catanzaro, Italy.
Davide PisaniUnit of Audiology, Department of Experimental and Clinical Medicine, Regional Centre of Cochlear Implants and ENT Diseases, Magna Graecia University, 88100 Catanzaro, Italy.ORCID 0000-0001-7486-0140
Vincenzo RaniaOperative Unit of Pharmacology and Pharmacovigilance, "Mater Domini" Hospital, Department of Health Science, University Magna Graecia, 88100 Catanzaro, Italy.
Alessandro CasarellaOperative Unit of Pharmacology and Pharmacovigilance, "Mater Domini" Hospital, Department of Health Science, University Magna Graecia, 88100 Catanzaro, Italy.ORCID 0000-0003-2294-0768
Alessia AstorinaUnit of Audiology, Department of Experimental and Clinical Medicine, Regional Centre of Cochlear Implants and ENT Diseases, Magna Graecia University, 88100 Catanzaro, Italy.
Alfonso ScarpaDepartment of Medicine and Surgery, University of Salerno, 84081 Baronissi, Italy.
Massimiliano EspositoDepartment of Medical, Surgical and Advanced Technologies "G.F. Ingrassia", University of Catania, 95121 Catania, Italy.ORCID 0000-0001-7880-3450
Monica SalernoDepartment of Medical, Surgical and Advanced Technologies "G.F. Ingrassia", University of Catania, 95121 Catania, Italy.
Nunzio Di NunnoDepartment of History, Society and Studies on Humanity, University of Salento, 73100 Lecce, Italy.
Matteo BolcatoLegal Medicine, University of Padua, 35121 Padova, Italy.ORCID 0000-0002-8784-8463
Amalia PiscopoForensic Medicine, Department of Law, Magna Graecia University of Catanzaro, 88100 Catanzaro, Italy.
Erika CioneDepartment of Pharmacy, Health and Nutritional Sciences, Department of Excellence 2018-2022, University of Calabria, 87036 Rende, Italy.ORCID 0000-0002-0562-0597
Giovambattista De SarroOperative Unit of Pharmacology and Pharmacovigilance, "Mater Domini" Hospital, Department of Health Science, University Magna Graecia, 88100 Catanzaro, Italy.
Giulio Di MizioForensic Medicine, Department of Law, Magna Graecia University of Catanzaro, 88100 Catanzaro, Italy.ORCID 0000-0001-7279-3693
Luca GallelliOperative Unit of Pharmacology and Pharmacovigilance, "Mater Domini" Hospital, Department of Health Science, University Magna Graecia, 88100 Catanzaro, Italy.ORCID 0000-0003-0858-7902
Magna Graecia University · ITUniversity of Catania · ITUniversity of Calabria · ITUniversity of Padua · ITUniversity of Salento · ITUniversity of Salerno · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vestibular disorders may generate complex signs and symptoms, which may alter patients' balance and the quality of life. Dizziness and vertigo can strongly affect daily activities and relations. Despite the presence of conventional drugs, maneuvers, and surgery, another interesting therapeutic opportunity is offered by nutraceuticals. These molecules are often used in the treatment of dizziness and vertigo, but the rationale of their application is not always solidly demonstrated by the scientific evidence. Several substances have shown a variable level of efficacy/usefulness in this field, but there is lack of important evidence for most of them. From a medico-legal point of view, specific information must be provided to the patient regarding the efficacy and possibilities that the use of these preparations can allow. Administering the right nutraceutical to the proper patient is a fundamental clinical skill. Integrating conventional drug treatment with nutraceutical administration seems to be easy, but it may be difficult considering the (in part unexplored) pharmacodynamics and pharmacokinetics of nutraceuticals. The aim of the scientific community should be to elevate nutraceuticals to the same law and technical dignity of conventional drugs.

Indexed as

Dietary SupplementsLegislation as TopicDizzinessHumansVertigoVestibule, Labyrinthclinical risk managementdizzinessnutraceuticalspatient’s safetytreatmentvertigovestibular

Identifiers

PMID34684646
PMCPMC8538675
OpenAlexW3205825844

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.