Evidence map›Paper›PMID 34684538›Full record

ArticleNutrients2021

Daily Leucine Intake Is Positively Associated with Lower Limb Skeletal Muscle Mass and Strength in the Elderly.

Manoel E Lixandrão, Igor Longobardi, Alice E Leitão, João V M Morais, Paul A Swinton, André Y Aihara, Paola C K Goes, Carlos Ugrinowitsch, Darren G Candow, Bruno Gualano and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 3 pooled it
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 3 syntheses or guidelines pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Review
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 3 countries.

Manoel E LixandrãoApplied Physiology and Nutrition Research Group, School of Physical Education and Sport, Rheumatology Division, Faculdade de Medicina FMUSP, University of São Paulo, São Paulo 01246-903, SP, Brazil.
Igor LongobardiApplied Physiology and Nutrition Research Group, School of Physical Education and Sport, Rheumatology Division, Faculdade de Medicina FMUSP, University of São Paulo, São Paulo 01246-903, SP, Brazil.
Alice E LeitãoApplied Physiology and Nutrition Research Group, School of Physical Education and Sport, Rheumatology Division, Faculdade de Medicina FMUSP, University of São Paulo, São Paulo 01246-903, SP, Brazil.ORCID 0000-0002-1169-6686
João V M MoraisApplied Physiology and Nutrition Research Group, School of Physical Education and Sport, Rheumatology Division, Faculdade de Medicina FMUSP, University of São Paulo, São Paulo 01246-903, SP, Brazil.
Paul A SwintonSchool of Health Sciences, Robert Gordon University, Aberdeen AB10 7QE, UK.
André Y AiharaLaboratório Delboni Auriemo, São Paulo 04037-005, SP, Brazil.ORCID 0000-0002-3194-9409
Paola C K GoesLaboratório Delboni Auriemo, São Paulo 04037-005, SP, Brazil.
Carlos UgrinowitschSchool of Physical Education and Sport, University of São Paulo, São Paulo 05508-030, SP, Brazil.
Darren G CandowFaculty of Kinesiology and Health Studies, University of Regina, Regina, SK S4S 0A2, Canada.
Bruno GualanoApplied Physiology and Nutrition Research Group, School of Physical Education and Sport, Rheumatology Division, Faculdade de Medicina FMUSP, University of São Paulo, São Paulo 01246-903, SP, Brazil.
Hamilton RoschelApplied Physiology and Nutrition Research Group, School of Physical Education and Sport, Rheumatology Division, Faculdade de Medicina FMUSP, University of São Paulo, São Paulo 01246-903, SP, Brazil.ORCID 0000-0002-9513-6132
Universidade de São Paulo · BRRobert Gordon University · GBUniversity of Regina · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Higher daily protein intake, with an emphasis on leucine content, is thought to mitigate age-related anabolic resistance, potentially counteracting age-related morphological and functional declines. The present study investigated potential associations between total daily leucine intake and dependent variables, including quadriceps muscle cross-sectional area (CSA) and maximum dynamic muscle strength (1-RM) in a cohort of healthy free-living older individuals of both sexes (

Indexed as

EatingAgedFemaleHumansLeucineLower ExtremityMaleMuscle, SkeletalMuscle StrengthRegression AnalysisLeucineagingessential amino acidsmuscle functionolder individualsprotein intake

Identifiers

PMID34684538
PMCPMC8539207
OpenAlexW3206412624

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.