Evidence map›Paper›PMID 34684464›Full record

ArticleNutrients2021

Metabolic Effects of Vitamin B1 Therapy under Overnutrition and Undernutrition Conditions in Sheep.

Mugagga Kalyesubula, Ramgopal Mopuri, Alexander Rosov, Guy Van Bommel, Hay Dvir

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Mugagga KalyesubulaAgricultural Research Organization-Volcani Institute, Institute of Animal Science, Rishon LeZion 7552809, Israel.ORCID 0000-0002-1100-263X
Ramgopal MopuriAgricultural Research Organization-Volcani Institute, Institute of Animal Science, Rishon LeZion 7552809, Israel.
Alexander RosovAgricultural Research Organization-Volcani Institute, Institute of Animal Science, Rishon LeZion 7552809, Israel.
Guy Van BommelAgricultural Research Organization-Volcani Institute, Institute of Animal Science, Rishon LeZion 7552809, Israel.
Hay DvirAgricultural Research Organization-Volcani Institute, Institute of Animal Science, Rishon LeZion 7552809, Israel.ORCID 0000-0002-5024-5626
Agricultural Research Organization · ILHebrew University of Jerusalem · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As a precursor for a universal metabolic coenzyme, vitamin B1, also known as thiamine, is a vital nutrient in all living organisms. We previously found that high-dose thiamine therapy prevents overnutrition-induced hepatic steatosis in sheep by enhancing oxidative catabolism. Based on this capacity, we hypothesized that thiamine might also reduce whole-body fat and weight. To test it, we investigated the effects of high-dose thiamine treatment in sheep under overnutrition and calorie-restricted undernutrition to respectively induce positive energy balance (PEB) and negative energy balance (NEB). Eighteen mature ewes were randomly assigned to three treatment groups (

Indexed as

Adipose TissueAnimalsBiomarkersBlood GlucoseBody WeightCreatinineEnergy MetabolismFatty AcidsLipid MetabolismLipolysisMalnutritionMicronutrientsMineralsOvernutritionSheepThiamineBiomarkersBlood GlucoseCreatinineFatty AcidsMicronutrientsMineralsThiaminebody weightmicronutrient therapyobesitysheepvitamin B1

Identifiers

PMID34684464
PMCPMC8540229
OpenAlexW3204858161

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.