Evidence map›Paper›PMID 34684451›Full record

SynthesisNutrients2021

Ramadan Fasting during Pregnancy and Health Outcomes in Offspring: A Systematic Review.

Violet N L Oosterwijk, Joyce M Molenaar, Lily A van Bilsen, Jessica C Kiefte-de Jong

Abstract readSystematic Review
In one paragraph

Synthesis in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Impacts of Ramadan fasting during pregnancy on pregnancy and birth outcomes: An umbrella review.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2025
    Pooled it
  3. Pooled it
  4. Trial
  5. Review
  6. Article
  7. Review
  8. Ramadan fasting intentions among pregnant women in Lebanon.The Journal of the Egyptian Public Health Association · 2024
    Article
  9. Article
  10. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Violet N L OosterwijkLeiden University College, Leiden University, 2595 DG The Hague, The Netherlands.
Joyce M MolenaarCentre for Nutrition, Prevention and Health Services, Department of Quality of Care and Health Economics, National Institute for Public Health and the Environment, 3721 MA Bilthoven, The Netherlands.
Lily A van BilsenLeiden University College, Leiden University, 2595 DG The Hague, The Netherlands.
Jessica C Kiefte-de JongDepartment of Public Health and Primary Care, LUMC-Campus, Leiden University Medical Center, 2511 DP The Hague, The Netherlands.ORCID 0000-0002-8136-0918

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ramadan is one of the five pillars of Islam, during which fasting is obligatory for all healthy individuals. Although pregnant women are exempt from this Islamic law, the majority nevertheless choose to fast. This review aims to identify the effects of Ramadan fasting on the offspring of Muslim mothers, particularly on fetal growth, birth indices, cognitive effects and long-term effects. A systematic literature search was conducted until March 2020 in Web of Science, Pubmed, Cochrane Library, Embase and Google Scholar. Studies were evaluated based on a pre-defined quality score ranging from 0 (low quality) to 10 (high quality), and 43 articles were included. The study quality ranged from 2 to 9 with a mean quality score of 5.4. Only 3 studies had a high quality score (>7), of which one found a lower birth weight among fasting women. Few medium quality studies found a significant negative effect on fetal growth or birth indices. The quality of articles that investigated cognitive and long-term effects was poor. The association between Ramadan fasting and health outcomes of offspring is not supported by strong evidence. To further elucidate the effects of Ramadan fasting, larger prospective and retrospective studies with novel designs are needed.

Indexed as

FastingHealth Impact AssessmentIslamMaternal ExposurePrenatal Exposure Delayed EffectsBiomarkersBirth WeightCognitionFemaleFetal DevelopmentHumansPregnancyPregnancy OutcomePublic Health SurveillanceBiomarkersfastingfetal developmenthumansinfantIslamnewbornpregnancypregnancy outcome

Identifiers

PMID34684451
PMCPMC8540108

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.