Evidence map›Paper›PMID 34684429›Full record

Trial reportNutrients2021

L-Carnitine Tartrate Supplementation for 5 Weeks Improves Exercise Recovery in Men and Women: A Randomized, Double-Blind, Placebo-Controlled Trial.

Matthew Stefan, Matthew Sharp, Raad Gheith, Ryan Lowery, Charlie Ottinger, Jacob Wilson, Shane Durkee, Aouatef Bellamine

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Matthew StefanApplied Science & Performance Institute, Research Division, Tampa, FL 33607, USA.
Matthew SharpApplied Science & Performance Institute, Research Division, Tampa, FL 33607, USA.ORCID 0000-0003-2018-9229
Raad GheithApplied Science & Performance Institute, Research Division, Tampa, FL 33607, USA.
Ryan LoweryApplied Science & Performance Institute, Research Division, Tampa, FL 33607, USA.
Charlie OttingerApplied Science & Performance Institute, Research Division, Tampa, FL 33607, USA.
Jacob WilsonApplied Science & Performance Institute, Research Division, Tampa, FL 33607, USA.
Shane DurkeeLonza Consumer Health Inc., Morristown, NJ 07960, USA.
Aouatef BellamineLonza Consumer Health Inc., Morristown, NJ 07960, USA.
Lonza (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

L-carnitine tartrate has been shown to improve relatively short-term recovery among athletes. However, there is a lack of research on the longer-term effects in the general population.

objectiveThe primary objectives of this randomized double-blind, placebo-controlled trial were to evaluate the effects of daily L-carnitine tartrate supplementation for 5 weeks on recovery and fatigue.

methodIn this study, eighty participants, 21- to 65-years-old, were recruited. Participants were split into two groups of forty participants each, a placebo, and a L-carnitine Tartrate group. Seventy-three participants completed a maintenance exercise training program that culminated in a high-volume exercise challenge.

resultsCompared to placebo, L-carnitine tartrate supplementation was able to improve perceived recovery and soreness (

conclusionsThese findings agree with previous observations among healthy adult subjects and demonstrate that L-carnitine tartrate supplementation beyond 35 days is beneficial for improving recovery and reducing fatigue following exercise across gender and age.

Indexed as

Dietary SupplementsExerciseAdultAge FactorsBiomarkersBody CompositionCarnitineFatigueFemaleHumansMaleMuscle, SkeletalMuscle StrengthSex FactorsSuperoxide DismutaseTartratesBiomarkersCarnitineSuperoxide DismutaseTartratescarnitineexercisefatigueL-carnitine tartratemuscle damage antioxidantmuscle powermuscle strengthrecovery

Identifiers

PMID34684429
PMCPMC8541253
OpenAlexW3202991132

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.