Evidence map›Paper›PMID 34684428›Full record

ArticleNutrients2021

From Mum to Bum: An Observational Study Protocol to Follow Digestion of Human Milk Oligosaccharides and Glycoproteins from Mother to Preterm Infant.

Jannie G E Henderickx, Esther J d'Haens, Marieke A C Hemels, Mariëtte E Schoorlemmer, Astrid Giezen, Richard A van Lingen, Jan Knol, Clara Belzer

Open access · goldAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Jannie G E HenderickxLaboratory of Microbiology, Wageningen University and Research, Stippeneng 4, 6708 WE Wageningen, The Netherlands.ORCID 0000-0001-6533-0324
Esther J d'HaensDepartment of Neonatology, Isala Women and Children's Hospital, Dokter van Heesweg 2, 8025 AB Zwolle, The Netherlands.
Marieke A C HemelsDepartment of Neonatology, Isala Women and Children's Hospital, Dokter van Heesweg 2, 8025 AB Zwolle, The Netherlands.
Mariëtte E SchoorlemmerDepartment of Neonatology, Isala Women and Children's Hospital, Dokter van Heesweg 2, 8025 AB Zwolle, The Netherlands.
Astrid GiezenDepartment of Neonatology, Isala Women and Children's Hospital, Dokter van Heesweg 2, 8025 AB Zwolle, The Netherlands.ORCID 0000-0002-3728-8525
Richard A van LingenDepartment of Neonatology, Isala Women and Children's Hospital, Dokter van Heesweg 2, 8025 AB Zwolle, The Netherlands.
Jan KnolLaboratory of Microbiology, Wageningen University and Research, Stippeneng 4, 6708 WE Wageningen, The Netherlands.ORCID 0000-0002-2103-5961
Clara BelzerLaboratory of Microbiology, Wageningen University and Research, Stippeneng 4, 6708 WE Wageningen, The Netherlands.
Isala · NLWageningen University & Research · NLDanone (Netherlands) · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The nutritional requirements of preterm infants are challenging to meet in neonatal care, yet crucial for their growth, development and health. Aberrant maturation of the gastrointestinal tract and the microbiota could affect the digestion of human milk and its nutritional value considerably. Therefore, the main objective of the proposed research is to investigate how the intestinal microbiota of preterm and full-term infants differ in their ability to extract energy and nutrients from oligosaccharides and glycoproteins in human milk. This pilot study will be an observational, single-center study performed at the Neonatal Intensive Care Unit at Isala Women and Children's Hospital (Zwolle, The Netherlands). A cohort of thirty mother-infant pairs (preterm ≤30 weeks of gestation,

Indexed as

DigestionGlycoproteinsInfant, PrematureMilk, HumanMilk ProteinsOligosaccharidesFemaleGastrointestinal MicrobiomeHumansInfantInfant FormulaInfant, NewbornInfant Nutritional Physiological PhenomenaObservational Studies as TopicProteomeProteomicsGlycoproteinsMilk ProteinsOligosaccharidesProteomefecesgastric aspiratehuman milkinfantmicrobiomemicrobiotanutritionpreterm

Identifiers

PMID34684428
PMCPMC8538091
OpenAlexW3203537442

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.