Evidence map›Paper›PMID 34684427›Full record

ArticleNutrients2021

Exploring the Advantages of a Hydrolyzed Rice Formula in the Dietary Management of Infants with Cow's Milk Allergy in the Middle East, North Africa, and Pakistan Region.

Yvan Vandenplas, Christophe Dupont, Wajeeh Al-Dekhail, Hani A Al Hashmi, Ahmed Fouad Khalil, Mostafa Abdel-Aziz El-Hodhod, Khaled Husain, Avantika Singh

Open access · goldAbstract readConference Proceedings
In one paragraph

Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Observational
  2. Article
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  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 5 countries.

Yvan VandenplasVrije Unversiteit Brussel (VUB), UZ Brussel, KidZ Health Castle, 1090 Brussels, Belgium.ORCID 0000-0002-1862-8651
Christophe DupontPediatric Gastroenterology Department, Paris-Descartes University, 75006 Paris, France.
Wajeeh Al-DekhailSection of Gastroenterology, Pediatrics Department, King Faisal Specialist Hospital & Research Centre, P.O. Box 3354, Riyadh 11211, Saudi Arabia.
Hani A Al HashmiSection of Allergy and Clinical Immunology, Pediatrics Department, King Abdulaziz Hospital, Jeddah 22421, Saudi Arabia.
Ahmed Fouad KhalilPediatric Gastroenterology and Nutrition Department, Alexandria University, Alexandria 21544, Egypt.
Mostafa Abdel-Aziz El-HodhodPediatric Gastroenterology and Endoscopy Department, Faculty of Medicine, Ain Shams University, Cairo 11535, Egypt.ORCID 0000-0003-0966-5466
Khaled HusainPediatric Gastroenterology, Hepatology and Nutrition Department, Dar AlShifa Hospital, Kuwait City 13034, Kuwait.
Avantika SinghPediatric Gastroenterology Department, Mediclinic Airport Road, Abu Dhabi 48481, United Arab Emirates.
Ain Shams University · EGAlexandria University · EGDélégation Paris 5 · FRKing Abdulaziz Hospital · SAKing Faisal Specialist Hospital & Research Centre · SAMediclinic City Hospital · AEVrije Universiteit Brussel · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cow's milk allergy (CMA) is the most common food allergy in early childhood, and its prevalence continues to rise. Exclusive breastfeeding is recommended for infants in the first 6 months of life, but this recommendation is poorly adhered to in many parts of the world, including the Middle East, North Africa, and Pakistan (MENAP) region. If the infant is affected by CMA, current guidelines recommend extensively hydrolyzed formulas (eHFs) or amino acid-based formulas (AAFs) in the case of severe symptoms, and hydrolyzed rice formulas (HRFs) where available. In recent years, HRFs have been proposed as a plant-based alternative to cow's milk protein-based eHFs, and updates to current guidelines have been recommended. In 2014, a consensus statement and guidelines were published for the Middle East region on the prevention, diagnosis, and management of CMA. As new advances have been made in the extensively hydrolyzed hypoallergenic infant formula space, along with updated scientific evidence, a workshop of experts from the MENAP region focused on HRF was convened in 2021. This publication summarizes the insights from this meeting. During the consensus part of the meeting, a new approach was discussed and approved by all participants, and agreement was reached that HRF can be recommended as a first-line alternative to cow's milk-based eHF in the dietary management of CMA.

Indexed as

Infant FormulaOryzaAfrica, NorthernAnimalsDisease ManagementDisease SusceptibilityHumansMiddle EastMilk HypersensitivityPakistanPublic Health Surveillancecow’s milk allergyhydrolyzed proteininfant allergyinfant feedingMiddle Eastrice

Identifiers

PMID34684427
PMCPMC8537404
OpenAlexW3202676762

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.