Evidence map›Paper›PMID 34684380›Full record

ArticleNutrients2021

The Fermented Soy Product ImmuBalance

Hideaki Kadotani, Kazuhisa Asai, Atsushi Miyamoto, Kohei Iwasaki, Takahiro Kawai, Misako Nishimura, Mitsunori Tohda, Atsuko Okamoto, Kanako Sato, Kazuhiro Yamada and 3 more

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Are Fermented Foods Effective against Inflammatory Diseases?International journal of environmental research and public health · 2023
    Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Hideaki KadotaniDepartment of Respiratory Medicine, Graduate School of Medicine, Osaka City University, Osaka 545-8585, Japan.ORCID 0000-0002-2532-9262
Kazuhisa AsaiDepartment of Respiratory Medicine, Graduate School of Medicine, Osaka City University, Osaka 545-8585, Japan.ORCID 0000-0001-8400-863X
Atsushi MiyamotoDepartment of Respiratory Medicine, Graduate School of Medicine, Osaka City University, Osaka 545-8585, Japan.
Kohei IwasakiDepartment of Respiratory Medicine, Graduate School of Medicine, Osaka City University, Osaka 545-8585, Japan.
Takahiro KawaiDepartment of Respiratory Medicine, Graduate School of Medicine, Osaka City University, Osaka 545-8585, Japan.
Misako NishimuraDepartment of Respiratory Medicine, Graduate School of Medicine, Osaka City University, Osaka 545-8585, Japan.
Mitsunori TohdaDepartment of Respiratory Medicine, Graduate School of Medicine, Osaka City University, Osaka 545-8585, Japan.
Atsuko OkamotoDepartment of Respiratory Medicine, Graduate School of Medicine, Osaka City University, Osaka 545-8585, Japan.
Kanako SatoDepartment of Respiratory Medicine, Graduate School of Medicine, Osaka City University, Osaka 545-8585, Japan.
Kazuhiro YamadaDepartment of Respiratory Medicine, Graduate School of Medicine, Osaka City University, Osaka 545-8585, Japan.
Naoki IjiriDepartment of Respiratory Medicine, Graduate School of Medicine, Osaka City University, Osaka 545-8585, Japan.
Tetsuya WatanabeDepartment of Respiratory Medicine, Graduate School of Medicine, Osaka City University, Osaka 545-8585, Japan.
Tomoya KawaguchiDepartment of Respiratory Medicine, Graduate School of Medicine, Osaka City University, Osaka 545-8585, Japan.
Osaka City University · JP

Funding

Japan Society for the Promotion of Science 19K08660
6 · The paper itself

Abstract

The fermented soy product ImmuBalance contains many active ingredients and its beneficial effects on some allergic diseases have been reported. We hypothesized that ImmuBalance could have potential effects on airway inflammation in a murine model of asthma. Mice sensitized and challenged with ovalbumin developed airway inflammation. Bronchoalveolar lavage fluid was assessed for inflammatory cell counts and levels of cytokines. Lung tissues were examined for cell infiltration and mucus hypersecretion. Oral administration of ImmuBalance significantly inhibited ovalbumin-induced eosinophilic inflammation and decreased Th2 cytokine levels in bronchoalveolar lavage fluid (

Indexed as

Fermented FoodsAnimalsAsthmaBody WeightBronchoalveolar Lavage FluidCell CountCytokinesDietDisease Models, AnimalEosinophilsFeeding BehaviorFemaleGlycine maxImmunoglobulin EInflammationLungCytokinesImmunoglobulin EOvalbuminasthmaeosinophilic inflammationfermented soy productTh2 cytokines

Identifiers

PMID34684380
PMCPMC8537480
OpenAlexW3202586277

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.