Evidence map›Paper›PMID 34684352›Full record

ArticleNutrients2021

Magnesium Picolinate Improves Bone Formation by Regulation of RANK/RANKL/OPG and BMP-2/Runx2 Signaling Pathways in High-Fat Fed Rats.

Emre Sahin, Cemal Orhan, Tansel Ansal Balci, Fusun Erten, Kazim Sahin

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Emre SahinDepartment of Animal Nutrition, Faculty of Veterinary Medicine, Firat University, Elazig 23119, Turkey.ORCID 0000-0001-7625-1883
Cemal OrhanDepartment of Animal Nutrition, Faculty of Veterinary Medicine, Firat University, Elazig 23119, Turkey.ORCID 0000-0003-4138-7689
Tansel Ansal BalciDepartment of Nuclear Medicine, School of Medicine, Firat University, Elazig 23119, Turkey.
Fusun ErtenDepartment of Veterinary Medicine, Pertek Sakine Genc Vocational School, Munzur University, Tunceli 62500, Turkey.
Kazim SahinDepartment of Animal Nutrition, Faculty of Veterinary Medicine, Firat University, Elazig 23119, Turkey.ORCID 0000-0001-9542-5244
Fırat University · TRMunzur University · TR

Funding

Fırat University FUBAP-VF. 19.08Turkish Academy of Sciences KS
6 · The paper itself

Abstract

Magnesium (Mg) deficiency may affect bone metabolism by increasing osteoclasts, decreasing osteoblasts, promoting inflammation/oxidative stress, and result in subsequent bone loss. The objective of the present study was to identify the molecular mechanism underlying the bone protective effect of different forms of Mg (inorganic magnesium oxide (MgO) versus organic magnesium picolinate (MgPic) compound) in rats fed with a high-fat diet (HFD). Forty-two Wistar albino male rats were divided into six group (

Indexed as

Feeding BehaviorOsteogenesisAnimalsBone and BonesBone DensityBone Morphogenetic Protein 2Core Binding Factor Alpha 1 SubunitDiet, High-FatElementsMaleOsteoprotegerinPicolinic AcidsRANK LigandRatsRats, WistarReceptor Activator of Nuclear Factor-kappa BBone Morphogenetic Protein 2Core Binding Factor Alpha 1 SubunitElementsOsteoprotegerinpicolinic acidPicolinic AcidsRANK LigandReceptor Activator of Nuclear Factor-kappa Bbonebone mineral densityhigh-fat dietmagnesium picolinateosteogenic proteins

Identifiers

PMID34684352
PMCPMC8538721
OpenAlexW3204583363

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.