Evidence map›Paper›PMID 34684310›Full record

ArticleNutrients2021

Increased Adiposity Appraised with CUN-BAE Is Highly Predictive of Incident Hypertension. The SUN Project.

Ligia J Dominguez, Carmen Sayón-Orea, Alfredo Gea, Estefania Toledo, Mario Barbagallo, Miguel A Martínez-González

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Ligia J DominguezGeriatric Unit, Department of Internal Medicine and Geriatrics, University of Palermo, 90127 Palermo, Italy.
Carmen Sayón-OreaDepartment of Preventive Medicine and Public Health, University of Navarra-IDISNA, 31008 Pamplona, Spain.
Alfredo GeaDepartment of Preventive Medicine and Public Health, University of Navarra-IDISNA, 31008 Pamplona, Spain.
Estefania ToledoDepartment of Preventive Medicine and Public Health, University of Navarra-IDISNA, 31008 Pamplona, Spain.ORCID 0000-0002-6263-4434
Mario BarbagalloGeriatric Unit, Department of Internal Medicine and Geriatrics, University of Palermo, 90127 Palermo, Italy.ORCID 0000-0002-1349-6530
Miguel A Martínez-GonzálezDepartment of Preventive Medicine and Public Health, University of Navarra-IDISNA, 31008 Pamplona, Spain.ORCID 0000-0002-3917-9808
Instituto de Salud Carlos III · ESUniversity of Palermo · ITHarvard University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Overweight and obesity are growing worldwide and strongly associated with hypertension. The Clínica Universidad de Navarra-Body Adiposity Estimator (CUN-BAE) index is proposed as an optimal indicator of body fatness. We aimed to investigate the association of body fat as captured by the CUN-BAE index with incident hypertension in a Mediterranean population. We assessed 15,950 participants of the SUN (Seguimiento Universidad de Navarra) prospective cohort (63.7% women) initially free of hypertension. Participants completed follow-up questionnaires biennially. A validated 136-item food-frequency questionnaire was administered at baseline. We used Cox models adjusted for multiple confounders. Among 12.3 years of median follow-up (interquartile range: 8.3, 15.0 years), 2160 participants reported having received a diagnosis of hypertension. We observed a strong direct association between progressively higher the CUN-BAE index at baseline and incident hypertension during follow-up in multivariable-adjusted models for men and women, even after further adjustment for BMI ≥ 30 kg/m

Indexed as

AdiposityAdultFemaleFollow-Up StudiesHumansHypertensionIncidenceMaleMiddle AgedMultivariate Analysisadiposityblood pressurebody fatcohort studiesCUN-BAEdiethypertensionobesityoverweight

Identifiers

PMID34684310
PMCPMC8537177
OpenAlexW3199359395

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.