Evidence map›Paper›PMID 34684289›Full record

ArticlePathogens (Basel, Switzerland)2021

Low Prevalence of HEV Infection and No Associated Risk of HEV Transmission from Mother to Child among Pregnant Women in Vietnam.

Pham Xuan Huy, Dang Thanh Chung, Dang Thuy Linh, Ngo Thu Hang, Sivaramakrishna Rachakonda, Srinivas Reddy Pallerla, Le Thi Kieu Linh, Hoang Van Tong, Le Minh Dung, Can Van Mao and 7 more

Open access · goldAbstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 6 institutions in 3 countries.

Pham Xuan HuyDepartment of Pathophysiology, Vietnam Military Medical University, Hanoi 100000, Vietnam.
Dang Thanh ChungDepartment of Pathophysiology, Vietnam Military Medical University, Hanoi 100000, Vietnam.
Dang Thuy LinhDepartment of Pathophysiology, Vietnam Military Medical University, Hanoi 100000, Vietnam.
Ngo Thu HangDepartment of Pathophysiology, Vietnam Military Medical University, Hanoi 100000, Vietnam.
Sivaramakrishna RachakondaInstitute of Tropical Medicine, Universitätsklinikum Tübingen, 72074 Tübingen, Germany.ORCID 0000-0002-2319-2821
Srinivas Reddy PallerlaInstitute of Tropical Medicine, Universitätsklinikum Tübingen, 72074 Tübingen, Germany.ORCID 0000-0003-1669-1515
Le Thi Kieu LinhInstitute of Tropical Medicine, Universitätsklinikum Tübingen, 72074 Tübingen, Germany.
Hoang Van TongDepartment of Pathophysiology, Vietnam Military Medical University, Hanoi 100000, Vietnam.ORCID 0000-0002-7170-8810
Le Minh DungTra Vinh Obstetrics and Pediatrics Hospital, Tra Vinh 940000, Vietnam.
Can Van MaoDepartment of Pathophysiology, Vietnam Military Medical University, Hanoi 100000, Vietnam.
Heiner WedemeyerDepartment of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, 30625 Hannover, Germany.
C-Thomas BockDepartment of Infectious Diseases, Division of Viral Gastroenteritis and Hepatitis Pathogens and Enteroviruses, Robert Koch Institute, 13353 Berlin, Germany.ORCID 0000-0002-2773-486X
Peter G KremsnerInstitute of Tropical Medicine, Universitätsklinikum Tübingen, 72074 Tübingen, Germany.
Le Huu SongVietnamese-German Center for Medical Research (VG-CARE), Hanoi 100000, Vietnam.
Bui Tien SyVietnamese-German Center for Medical Research (VG-CARE), Hanoi 100000, Vietnam.
Nguyen Linh ToanDepartment of Pathophysiology, Vietnam Military Medical University, Hanoi 100000, Vietnam.
Thirumalaisamy P VelavanInstitute of Tropical Medicine, Universitätsklinikum Tübingen, 72074 Tübingen, Germany.ORCID 0000-0002-9809-9883
Vietnam Military Medical University · VNUniversitätsklinikum Tübingen · DEVietnamese - German Center of Excellence in Medical Research · VNMedizinische Hochschule Hannover · DERobert Koch Institute · DETra Vinh University · VN

Funding

Federal Ministry of Education and Research BMBF01DP19006AMinistry of Science and Technology MOST-ID: NĐT/DE/21/07
6 · The paper itself

Abstract

Infections with HEV in low- and middle-income countries (LMICs) are associated with increased rates of preterm birth, miscarriage, and stillbirth. The aim of the present study was to investigate HEV infections in pregnant women and the possibility of mother-to-child transmission, and associated outcomes. A total of 183 pregnant women in their third trimester were recruited and followed until delivery. Anti-HEV IgG and IgM were determined via enzyme-linked immunosorbent assay (ELISA), and HEV nucleic acids were detected in stool and cord blood samples. HEV genotypes were identified by Sanger sequencing, and phylogenetic analyses were performed. Mother-to-child transmission and associated adverse outcomes were not observed. Only 2% of patients (

Indexed as

hepatitis E virusHEV-3mother-to-child-transmissionpregnant womenzoonoses

Identifiers

PMID34684289
PMCPMC8539026
OpenAlexW3205601475

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.