Evidence map›Paper›PMID 34684284›Full record

ArticlePathogens (Basel, Switzerland)2021

Maca against Echinococcosis?-A Reverse Approach from Patient to In Vitro Testing.

Tanja Karpstein, Sheena Chaudhry, Solange Bresson-Hadni, Michael Hayoz, Ghalia Boubaker, Andrew Hemphill, Reto Rufener, Marc Kaethner, Isabelle Schindler, Yolanda Aebi and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pathogens (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Evaluation of the Protoscolicidal Activity ofEvidence-based complementary and alternative medicine : eCAM · 2024
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 2 countries.

Tanja KarpsteinDepartment of Infectious Diseases and Pathobiology (DIP), Institute of Parasitology, Vetsuisse Faculty, University of Bern, 3012 Bern, Switzerland.
Sheena ChaudhryDepartment of Infectious Diseases and Pathobiology (DIP), Institute of Parasitology, Vetsuisse Faculty, University of Bern, 3012 Bern, Switzerland.
Solange Bresson-HadniFrench National Reference Center for Echinococcosis, Parasitology-Mycology Laboratory, Besançon University Hospital, University Bourgogne Franche-Comté, 25000 Besançon, France.
Michael HayozDepartment of Clinical Chemistry & Center for Laboratory Medicine, Bern University Hospital (Inselspital), 3010 Bern, Switzerland.
Ghalia BoubakerDepartment of Infectious Diseases and Pathobiology (DIP), Institute of Parasitology, Vetsuisse Faculty, University of Bern, 3012 Bern, Switzerland.
Andrew HemphillDepartment of Infectious Diseases and Pathobiology (DIP), Institute of Parasitology, Vetsuisse Faculty, University of Bern, 3012 Bern, Switzerland.ORCID 0000-0002-0622-2128
Reto RufenerDepartment of Infectious Diseases and Pathobiology (DIP), Institute of Parasitology, Vetsuisse Faculty, University of Bern, 3012 Bern, Switzerland.ORCID 0000-0001-5952-7585
Marc KaethnerDepartment of Infectious Diseases and Pathobiology (DIP), Institute of Parasitology, Vetsuisse Faculty, University of Bern, 3012 Bern, Switzerland.
Isabelle SchindlerDepartment of Clinical Chemistry & Center for Laboratory Medicine, Bern University Hospital (Inselspital), 3010 Bern, Switzerland.
Yolanda AebiDepartment of Clinical Chemistry & Center for Laboratory Medicine, Bern University Hospital (Inselspital), 3010 Bern, Switzerland.
Antonio Sa CunhaCentre Hépato-Biliaire, Assistance Publique Hôpitaux de Paris Hôpital Paul Brousse, 94800 Villejuif, France.ORCID 0000-0003-4015-5368
Carlo R LargiadèrDepartment of Clinical Chemistry & Center for Laboratory Medicine, Bern University Hospital (Inselspital), 3010 Bern, Switzerland.
Britta Lundström-StadelmannDepartment of Infectious Diseases and Pathobiology (DIP), Institute of Parasitology, Vetsuisse Faculty, University of Bern, 3012 Bern, Switzerland.ORCID 0000-0003-2672-5766
University of Bern · CHUniversity Hospital of Bern · CHAssistance Publique – Hôpitaux de Paris · FRUniversity Hospital of Geneva · CH

Funding

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung 192072
6 · The paper itself

Abstract

Drug-based treatment of alveolar echinococcosis (AE) with benzimidazoles is in most cases non-curative, thus has to be taken lifelong. Here, we report on a 56-year-old male AE patient who received standard benzimidazole treatment and biliary plastic stents, and additionally self-medicated himself with the Peruvian plant extract Maca (

Indexed as

alveolar echinococcosisEchinococcus multilocularisLepidium meyeniiMacamedicinal plantmetabolite levelsphytotherapytreatmentUHPLC-MS/MS

Identifiers

PMID34684284
PMCPMC8537204
OpenAlexW3207974972

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.