Evidence map›Paper›PMID 34684195›Full record

ArticlePathogens (Basel, Switzerland)2021

Recognition of Long-COVID-19 Patients in a Canadian Tertiary Hospital Setting: A Retrospective Analysis of Their Clinical and Laboratory Characteristics.

Robert Kozak, Susan M Armstrong, Elsa Salvant, Claudia Ritzker, Jordan Feld, Mia J Biondi, Hubert Tsui

Open access · goldAbstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
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  10. Impact of sex and gender on post-COVID-19 syndrome, Switzerland, 2020.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Robert KozakSunnybrook Health Sciences Centre, Biological Science Platform, Sunnybrook Research Institute, Toronto, ON M4N 3M5, Canada.
Susan M ArmstrongSunnybrook Health Sciences Centre, Biological Science Platform, Sunnybrook Research Institute, Toronto, ON M4N 3M5, Canada.
Elsa SalvantSunnybrook Health Sciences Centre, Biological Science Platform, Sunnybrook Research Institute, Toronto, ON M4N 3M5, Canada.ORCID 0000-0002-5650-4748
Claudia RitzkerSunnybrook Health Sciences Centre, Biological Science Platform, Sunnybrook Research Institute, Toronto, ON M4N 3M5, Canada.
Jordan FeldToronto Centre for Liver Disease, University Health Network, Toronto, ON M5G 2C4, Canada.
Mia J BiondiToronto Centre for Liver Disease, University Health Network, Toronto, ON M5G 2C4, Canada.ORCID 0000-0002-1409-9908
Hubert TsuiSunnybrook Health Sciences Centre, Biological Science Platform, Sunnybrook Research Institute, Toronto, ON M4N 3M5, Canada.
Sunnybrook Health Science Centre · CAUniversity Health Network · CA

Funding

Sunnybrook Foundation & Sunnybrook Research Institute COVID-19 Research Initiative. N/A
6 · The paper itself

Abstract

A proportion of patients with COVID-19 have symptoms past the acute disease phase, which may affect quality of life. It is important for clinicians to be aware of this "long-COVID-19" syndrome to better diagnose, treat, and prevent it. We reviewed clinical and laboratory characteristics of a COVID-19 cohort in a Toronto, Ontario tertiary care center. Demographic, clinical, and laboratory data were collected, and patients were classified as "long-COVID-19" or "non-long-COVID-19" using consensus criteria. Of 397 patients who tested positive for COVID-19, 223 met inclusion criteria, and 62 (27%) had long-COVID-19. These patients had a similar age distribution compared to non-long-COVID-19 patients overall but were younger in the admitted long COVID-19 group. The long-COVID-19 group had more inpatients compared to the non-long-COVID-19 group (39% vs. 25%) and more frequent supplemental oxygen or mechanical ventilation use. However, long-COVID-19 patients did not differ by duration of mechanical ventilation, length of stay, comorbidities, or values of common laboratory tests ordered. The most frequent symptoms associated with long-COVID-19 were fatigue and weakness, as reported most commonly by the infectious disease, respirology and cardiology disciplines. In conclusion, by retrospective chart review, 27% of COVID-19 patients presenting to a tertiary care center in Toronto, Canada, were found to meet criteria for long-COVID-19. Past medical history and routine laboratory testing at presentation did not predict for long-COVID-19 development.

Indexed as

disease biomarkerslong-COVIDlong-haulersretrospective analysisSARS-CoV-2

Identifiers

PMID34684195
PMCPMC8537802
OpenAlexW3203148027

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.