Evidence map›Paper›PMID 34684144›Full record

ArticleMedicina (Kaunas, Lithuania)2021

Cannabis Dopaminergic Effects Induce Hallucinations in a Patient with Parkinson's Disease.

Katie Pizzolato, David Thacker, Nicole Del Toro-Pagán, Abeer Hanna, Jacques Turgeon, Adriana Matos, Nishita Amin, Veronique Michaud

Open access · goldAbstract readCase Reports
In one paragraph

Article in Medicina (Kaunas, Lithuania), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Katie PizzolatoOffice of Translational Research and Residency Programs, Tabula Rasa HealthCare, Moorestown, NJ 08057, USA.
David ThackerTabula Rasa HealthCare, Precision Pharmacotherapy Research and Development Institute, Tabula Rasa HealthCare, Orlando, FL 32827, USA.
Nicole Del Toro-PagánOffice of Translational Research and Residency Programs, Tabula Rasa HealthCare, Moorestown, NJ 08057, USA.
Abeer HannaViecare Butler, Program of All-Inclusive Care for the Elderly (PACE), Butler, PA 16001, USA.
Jacques TurgeonTabula Rasa HealthCare, Precision Pharmacotherapy Research and Development Institute, Tabula Rasa HealthCare, Orlando, FL 32827, USA.ORCID 0000-0002-7978-9280
Adriana MatosOffice of Translational Research and Residency Programs, Tabula Rasa HealthCare, Moorestown, NJ 08057, USA.ORCID 0000-0002-7448-9799
Nishita AminOffice of Translational Research and Residency Programs, Tabula Rasa HealthCare, Moorestown, NJ 08057, USA.
Veronique MichaudTabula Rasa HealthCare, Precision Pharmacotherapy Research and Development Institute, Tabula Rasa HealthCare, Orlando, FL 32827, USA.
Research & Development Institute · USVA Butler Healthcare · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cannabis products that contain the tetrahydrocannabinol (THC) cannabinoid are emerging as promising therapeutic agents for the treatment of medical conditions such as chronic pain. THC elicits psychoactive effects through modulation of dopaminergic neurons, thereby altering levels of dopamine in the brain. This case report highlights the complexity associated with medicinal cannabis and the health risks associated with its use. A 57-year-old male with Parkinson's disease was experiencing worsening tremors and vivid hallucinations despite therapy optimization attempts. It was discovered that the patient took cannabis for chronic back pain, and a pharmacogenomics (PGx) test indicated the presence of variants for the

Indexed as

CannabisParkinson DiseaseDopamine AgentsDronabinolHallucinationsHumansMiddle AgedDopamine AgentsDronabinolcannabisCOMTCYP2C9hallucinationsParkinson’s diseasepharmacogenomics

Identifiers

PMID34684144
PMCPMC8539120
OpenAlexW3207204432

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.