Evidence map›Paper›PMID 34684117›Full record

ReviewMedicina (Kaunas, Lithuania)2021

An Updated Review of Pemphigus Diseases.

Ali M Malik, Sarah Tupchong, Simo Huang, Abhirup Are, Sylvia Hsu, Kiran Motaparthi

Open access · goldAbstract readReview
In one paragraph

Review in Medicina (Kaunas, Lithuania), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed, 2 pooled it
11.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 2 syntheses or guidelines pooled it, 115 citations in OpenAlex.

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  19. Cellular therapies in rheumatic and musculoskeletal diseases.Journal of translational autoimmunity · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Ali M MalikCollege of Medicine, University of Florida, Gainesville, FL 32606, USA.ORCID 0000-0002-5898-8440
Sarah TupchongLewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, USA.
Simo HuangDepartment of Dermatology, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, USA.ORCID 0000-0003-3318-0143
Abhirup AreCollege of Medicine, University of Florida, Gainesville, FL 32606, USA.
Sylvia HsuDepartment of Dermatology, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, USA.
Kiran MotaparthiDepartment of Dermatology, College of Medicine, University of Florida, Gainesville, FL 32606, USA.ORCID 0000-0003-0562-0826
Temple University · USUniversity of Florida · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Clinicians may encounter a variety of skin conditions that present with vesiculobullous lesions in their everyday practice. Pemphigus vulgaris, pemphigus foliaceus, IgA pemphigus, and paraneoplastic pemphigus represent the spectrum of autoimmune bullous dermatoses of the pemphigus family. The pemphigus family of diseases is characterized by significant morbidity and mortality. Considering the risks associated with a delayed diagnosis or misdiagnosis and the potential for overlap in clinical features and treatment, evaluation for suspected pemphigus disease often requires thorough clinical assessment and laboratory testing. Diagnosis is focused on individual biopsies for histopathology and direct immunofluorescence. Additional laboratory methods used for diagnosis include indirect immunofluorescence and enzyme-linked immunosorbent assay. Recent advancements, including anti-CD20 therapy, have improved the efficacy and reduced the morbidity of pemphigus treatment. This contribution presents updates on the pathophysiology, clinical features, diagnostic work-up, and medical management of pemphigus. Improved strategies for diagnosis and clinical assessment are reviewed, and newer treatment options are discussed.

Indexed as

Autoimmune DiseasesPemphigusSkin Diseases, VesiculobullousEnzyme-Linked Immunosorbent AssayFluorescent Antibody Technique, IndirectHumansIgA pemphiguspemphiguspemphigus dermatosespemphigus foliaceuspemphigus vulgaris

Identifiers

PMID34684117
PMCPMC8540565
OpenAlexW3205443007

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.