ReviewMedicina (Kaunas, Lithuania)2021
Pustular Psoriasis and Acute Generalized Exanthematous Pustulosis.
Review in Medicina (Kaunas, Lithuania), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.
- Monotherapy with Biologics for Generalized Pustular Psoriasis: A Systematic Review of Comparative Interventional Studies with an Exploratory Network Meta-Analysis.Medical sciences (Basel, Switzerland) · 2026Pooled it
- The Role of Genetic Testing in the Differential Diagnosis of Pustular Dermatoses: A Pediatric Case of Generalized Pustular Psoriasis Associated with the IL36RN Variant.Journal of clinical medicine · 2026Article
- Infliximab-induced paradoxical psoriasis successfully treated with secukinumab: A case report.SAGE open medical case reports · 2026Article
- Article
- A Rare Presentation of Acute Generalized Exanthematous Pustulosis With Refractory Shock.Cureus · 2025Article
- Single-cell immunopathology of recurrent acute generalized exanthematous pustulosis associated with vancomycin.The journal of allergy and clinical immunology. Global · 2025Article
- Considerations for defining and diagnosing generalized pustular psoriasis.Journal of the European Academy of Dermatology and Venereology : JEADV · 2025Review
- Widespread pustular rash in an elderly patient.JAAD case reports · 2025Article
- Risk Factors for Drug-Induced Acute Generalized Exanthematous Pustulosis(AGEP) from 2004 to 2024: A Real-World Study Based on the FAERS.Clinical, cosmetic and investigational dermatology · 2025Article
- Isotretinoin - Induced AGEP: A Case Report.International medical case reports journal · 2025Article
- Denosumab-induced Acute Generalized Exanthematous Pustulosis.Acta dermato-venereologica · 2024Article
- Acute generalized exanthematous pustulosis following ceftriaxone.Indian journal of pharmacology · 2024Article
- Article
- Acute Generalized Exanthematous Pustulosis: Clinical Features, Differential Diagnosis, and Management.American journal of clinical dermatology · 2023Review
- Generalized Pustular Psoriasis: A Review on Clinical Characteristics, Diagnosis, and Treatment.Dermatology and therapy · 2023Review
- Exploring the Clinical Features, Immunopathogenesis and Approach to Diagnosis for Generalized Pustular Psoriasis [Podcast].Clinical, cosmetic and investigational dermatology · 2023Article
- Severe Cutaneous Adverse Reaction Caused by Carbamazepine and Levofloxacin After Varicella Zoster Virus Infection.Infection and drug resistance · 2023Article
- A Case Report of Possibly Related Acute Generalized Exanthematous Pustulosis withClinical, cosmetic and investigational dermatology · 2023Article
- Terbinafine Induced Acute Generalized Exanthematous Pustulosis Treated with Adalimumab: Recalcitrant to Systemic Corticosteroid Therapy.Clinical, cosmetic and investigational dermatology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The similarity between pustular psoriasis (PP) and acute generalized exanthematous pustulosis (AGEP) poses problems in the diagnosis and treatment of these two conditions. Significant clinical and histopathologic overlap exists between PP and AGEP. PP is an inflammatory disorder that has numerous clinical subtypes, but all with sterile pustules composed of neutrophils. AGEP is a severe cutaneous adverse reaction that is also characterized by non-follicular sterile pustules. Clinical features that suggest a diagnosis of PP over AGEP include a history of psoriasis and the presence of scaling plaques. Histologically, eosinophilic spongiosis, vacuolar interface dermatitis, and dermal eosinophilia favor a diagnosis of AGEP over PP. Importantly, PP and AGEP vary in clinical course and treatment. PP treatment involves topical steroids, oral retinoids, and systemic immunosuppressants. Newer therapies targeting IL-36, IL-23, IL-1, and PDE-4 have been investigated. The removal of the offending agent is a crucial part of the treatment of AGEP.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.