Evidence map›Paper›PMID 34684034›Full record

ArticleMedicina (Kaunas, Lithuania)2021

Pathophysiology of Vaccine-Induced Prothrombotic Immune Thrombocytopenia (VIPIT) and Vaccine-Induced Thrombocytopenic Thrombosis (VITT) and Their Diagnostic Approach in Emergency.

Pierpaolo Di Micco, Giuseppe Camporese, Giuseppe Cardillo, Corrado Lodigiani, Novella Carannante, Anna Annunziata, Giuseppe Fiorentino, Vincenzo Russo, Egidio Imbalzano

Open access · goldAbstract read
In one paragraph

Article in Medicina (Kaunas, Lithuania), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
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  9. Post COVID-19 vaccination headache: A clinical and epidemiological evaluation.Frontiers in pain research (Lausanne, Switzerland) · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 7 institutions in 1 country.

Pierpaolo Di MiccoUOC Medicina, Ospedale Buon Consiglio Fatebenefratelli, 80122 Napoli, Italy.ORCID 0000-0002-8484-4598
Giuseppe CamporeseUnit of Angiology, Azienda Ospedaliera di Padova, 35100 Padova, Italy.ORCID 0000-0002-0881-5429
Giuseppe CardilloMedylab, Lusciano, 80100 Napoli, Italy.ORCID 0000-0001-6414-8475
Corrado LodigianiThrombosis and Haemorragic Diseases Unit, IRCCS Humanitas Research Hospital, 20089 Milan, Italy.ORCID 0000-0002-9152-9385
Novella CarannanteEmergency Unit, Ospedale D. Cotugno, 80131 Napoli, Italy.
Anna AnnunziataDepartment of Cardiology, OspedaleMonaldi, 80131 Napoli, Italy.
Giuseppe FiorentinoDepartment of Cardiology, OspedaleMonaldi, 80131 Napoli, Italy.ORCID 0000-0002-2523-9769
Vincenzo RussoHead of Cardiology, University of Campania "Luigi Vanvitelli", 80100 Napoli, Italy.ORCID 0000-0002-9227-0360
Egidio ImbalzanoDepartment of Cardiology, University of Messina, 98100 Messina, Italy.ORCID 0000-0003-2656-5467
Ospedale Monaldi · ITAzienda Ospedale - Università Padova · ITIRCCS Humanitas Research Hospital · ITOspedale Buon Consiglio Fatebenefratelli · ITOspedale D. Cotugno · ITUniversity of Campania "Luigi Vanvitelli" · ITUniversity of Messina · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

SARS-CoV-2 induced a pandemic that is reported to have started in Asia and was then extended to other countries in the world. Main clinical aspects of this viral infection have been lung injuries with severe pneumonia requiring prolonged hospitalization and associated morbidities such as venous thromboembolism and/or superinfection by bacteria, fungus or other pests. Immediately there was a need to develop a sustainable therapeutic strategy, such as vaccination. Vaccines against Covid-19, in fact, exert a protective action for common people and reduce viral diffusion. Yet, vaccination of a large number of people raises the question of a well-known complication of several types of vaccines; this complication is immune thrombocytopenia, which is sometimes associated with thrombosis as well. In this short review, we summarized mechanisms involved in the pathogenesis of vaccine-induced prothrombotic immune thrombocytopenia and vaccine-induced thrombocytopenic thrombosis.

Indexed as

COVID-19Purpura, Thrombocytopenic, IdiopathicThrombosisVaccinesCOVID-19 VaccinesHumansSARS-CoV-2COVID-19 VaccinesVaccinesanti-SARS-CoV-2 vaccineCOVID-19pandemicSARS-CoV-2vaccine

Identifiers

PMID34684034
PMCPMC8539999
OpenAlexW3199304562

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.