ArticlePharmaceutics2021
Deaggregation and Crystallization Inhibition by Small Amount of Polymer Addition for a Co-Amorphous Curcumin-Magnolol System.
Article in Pharmaceutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 49 citations in OpenAlex.
- Amorphous Solid Dispersions of Polyphenols: Current State of the Art (Part I).Pharmaceuticals (Basel, Switzerland) · 2026Review
- Dissolution Amelioration by Small Amounts of HPMC in the Difficult-to-solve Drug Combination Baicalein-imperatorin Co-Amorphous System: Dispersion and Crystallization Inhibition.AAPS PharmSciTech · 2025Article
- Structural and Spectroscopic Properties of Magnolol and Honokiol-Experimental and Theoretical Studies.International journal of molecular sciences · 2025Article
- Enhanced solubility and bioavailability of coenzyme Q10 via co-amorphous system using stevioside.NPJ science of food · 2025Article
- Preparation and Characterization of Vitamin D3-Based Binary Amorphous Systems.Foods (Basel, Switzerland) · 2025Article
- A New Screening Strategy for Flavonoid Components to Obtain a Satisfactory Co-Amorphous System with Piperine.AAPS PharmSciTech · 2025Article
- Curcumin Solubility and Bioactivity Enhancement Through Amorphization with Tryptophan via Supercritical Fluid Technology.International journal of molecular sciences · 2025Article
- A drug-drug co-amorphous system for highly improved solubility of breviscapine: an experimental and computational study.Scientific reports · 2024Article
- Computational Support to Explore Ternary Solid Dispersions of Challenging Drugs Using Coformer and Hydroxypropyl Cellulose.Molecular pharmaceutics · 2024Article
- Polymers Enhance Chlortetracycline Hydrochloride Solubility.International journal of molecular sciences · 2024Article
- Preparation and Characterization of Lutein Co-Amorphous Formulation with Enhanced Solubility and Dissolution.Foods (Basel, Switzerland) · 2024Article
- Considerations on the Kinetic Processes in the Preparation of Ternary Co-Amorphous Systems by Milling.Pharmaceutics · 2023Article
- Ammonio Methacrylate Copolymer (Type B)-Diltiazem Interactions in Solid Dispersions andPolymers · 2022Article
- Benchmarking the Solubility Enhancement and Storage Stability of Amorphous Drug-Polyelectrolyte Nanoplex against Co-Amorphous Formulation of the Same Drug.Pharmaceutics · 2022Article
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
Different from previously reported co-amorphous systems, a co-amorphous curcumin-magnolol (CUR-MAG CM) system, as compared with its crystalline counterparts, exhibited decreased dissolution due to its aggregation during dissolution. The main purpose of the present study is to deaggregate CUR-MAG CM to optimize drug dissolution and explore the deaggregation mechanism involved. Herein, a small amount of polymer (HPMC, HPC, and PVP K30) was co-formulated at 5% (
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