Evidence map›Paper›PMID 34683927›Full record

ArticlePharmaceutics2021

Development, Characterization, and Clinical Investigation of a New Topical Emulsion System Containing a

Tiziana Esposito, Teresa Mencherini, Francesca Sansone, Giulia Auriemma, Patrizia Gazzerro, Rosa Valentina Puca, Raffaele Iandoli, Rita Patrizia Aquino

Abstract read
In one paragraph

Article in Pharmaceutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Review
  3. Valorization of Hazelnut (Antioxidants (Basel, Switzerland) · 2025
    Article
  4. Use of a novel indentometer to evaluate skin stiffness in healthy and diseased human skin.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2023
    Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Tiziana EspositoDepartment of Pharmacy, University of Salerno, 84084 Fisciano, Italy.
Teresa MencheriniDepartment of Pharmacy, University of Salerno, 84084 Fisciano, Italy.ORCID 0000-0001-8207-0085
Francesca SansoneDepartment of Pharmacy, University of Salerno, 84084 Fisciano, Italy.ORCID 0000-0002-3589-5196
Giulia AuriemmaDepartment of Pharmacy, University of Salerno, 84084 Fisciano, Italy.ORCID 0000-0001-9547-0969
Patrizia GazzerroDepartment of Pharmacy, University of Salerno, 84084 Fisciano, Italy.ORCID 0000-0003-0576-2955
Rosa Valentina PucaDermatology and Dermosurgery, "San Giuseppe Moscati" National Hospital (AORN), Contrada Amoretta, 83100 Avellino, Italy.
Raffaele IandoliDermatology and Dermosurgery, "San Giuseppe Moscati" National Hospital (AORN), Contrada Amoretta, 83100 Avellino, Italy.
Rita Patrizia AquinoDepartment of Pharmacy, University of Salerno, 84084 Fisciano, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The study focused on the development and characterization of an O/W emulsion for skincare containing

Indexed as

chestnut spiny burs extractclinical trialsin vivo skin performanceO/W emulsion systemself-assessment testskin compatibility

Identifiers

PMID34683927
PMCPMC8539921

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.