Evidence map›Paper›PMID 34683388›Full record

ArticleMicroorganisms2021

Pharmacokinetic Variability and Target Attainment of Fluconazole in Critically Ill Patients.

Ruth Van Daele, Joost Wauters, Katrien Lagrou, Raphaël Denooz, Marie-Pierre Hayette, Matthias Gijsen, Roger J Brüggemann, Yves Debaveye, Isabel Spriet

Open access · goldAbstract read
In one paragraph

Article in Microorganisms, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Ruth Van DaeleClinical Pharmacology and Pharmacotherapy, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, 3000 Leuven, Belgium.ORCID 0000-0002-8353-2103
Joost WautersLaboratory for Clinical Infectious and Inflammatory Disorders, Department of Microbiology, Immunology and Transplantation, KU Leuven, 3000 Leuven, Belgium.
Katrien LagrouClinical Department of Laboratory Medicine and National Reference Centre for Mycosis, Excellence Centre for Medical Mycology (ECMM), University Hospitals Leuven, 3000 Leuven, Belgium.ORCID 0000-0001-8668-1350
Raphaël DenoozLaboratory of Clinical, Forensic, Environmental and Industrial Toxicology, CHU Sart-Tilman, University of Liège, 4000 Liège, Belgium.
Marie-Pierre HayetteLaboratory of Clinical Microbiology, Centre for Interdisciplinary Research on Medicines (CIRM), University of Liège, 4000 Liège, Belgium.
Matthias GijsenClinical Pharmacology and Pharmacotherapy, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, 3000 Leuven, Belgium.ORCID 0000-0003-1378-3772
Roger J BrüggemannDepartment of Pharmacy and Radboud Institute for Health Sciences, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.
Yves DebaveyeLaboratory of Intensive Care Medicine, Department of Cellular and Molecular Medicine, KU Leuven, 3000 Leuven, Belgium.ORCID 0000-0003-1784-8297
Isabel SprietClinical Pharmacology and Pharmacotherapy, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, 3000 Leuven, Belgium.
KU Leuven · BEUniversity of Liège · BERadboud University Nijmegen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

critically ill patientsexposurefluconazolepharmacokineticstarget attainmentvariability

Identifiers

PMID34683388
PMCPMC8538061
OpenAlexW3204319807

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.