Evidence map›Paper›PMID 34683298›Full record

ArticleMicromachines2021

Growth and Drug Interaction Monitoring of NIH 3T3 Cells by Image Analysis and Capacitive Biosensor.

Gayoung Lee, Jaehun Jeong, Yeeun Kim, Dahyun Kang, Sooyong Shin, Jongwon Lee, Sung Ho Jeon, Moongyu Jang

Abstract read
In one paragraph

Article in Micromachines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Quantitative ICBiosensors · 2025
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Gayoung LeeSchool of Nano Convergence Technology, Hallym University, Chuncheon 24252, Korea.ORCID 0000-0002-7106-7785
Jaehun JeongSchool of Nano Convergence Technology, Hallym University, Chuncheon 24252, Korea.
Yeeun KimSchool of Nano Convergence Technology, Hallym University, Chuncheon 24252, Korea.ORCID 0000-0001-8170-316X
Dahyun KangSchool of Nano Convergence Technology, Hallym University, Chuncheon 24252, Korea.ORCID 0000-0001-7784-826X
Sooyong ShinDepartment of Life Science and Multidisciplinary Institute, Hallym University, Chuncheon 24252, Korea.
Jongwon LeeDepartment of Life Science and Multidisciplinary Institute, Hallym University, Chuncheon 24252, Korea.
Sung Ho JeonDepartment of Life Science and Multidisciplinary Institute, Hallym University, Chuncheon 24252, Korea.ORCID 0000-0001-5982-140X
Moongyu JangSchool of Nano Convergence Technology, Hallym University, Chuncheon 24252, Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Capacitive biosensors are manufactured on glass slides using the semiconductor process to monitor cell growth and cell-drug interactions in real time. Capacitance signals are continuously monitored for each 10 min interval during a 48 h period, with the variations of frequency from 1 kHz to 1 MHz. The capacitance values showed a gradual increase with the increase in NIH 3T3 cell numbers. After 48 h of growth, 6.67 μg/mL puromycin is injected for the monitoring of the cell-drug interaction. The capacitance values rapidly increased during a period of about 10 h, reflecting the rapid increase in the cell numbers. In this study, we monitored the state of cells and the cell-drug interactions using the developed capacitive biosensor. Additionally, we monitored the state of cell behavior using a JuLi

Indexed as

capacitive biosensorcell–drug interactioncell growthNIH 3T3 cellreal-time monitoring

Identifiers

PMID34683298
PMCPMC8540853

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.