Evidence map›Paper›PMID 34683261›Full record

ArticleMicromachines2021

Performance Evaluation of a Magnetically Driven Microrobot for Targeted Drug Delivery.

Zhuocong Cai, Qiang Fu, Songyuan Zhang, Chunliu Fan, Xi Zhang, Jian Guo, Shuxiang Guo

Abstract read
In one paragraph

Article in Micromachines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. A Magnetically Capsule Robot for Biomedical Application.Applied bionics and biomechanics · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zhuocong CaiIntelligent Robot Laboratory, Tianjin University of Technology, Tianjin 300380, China.ORCID 0000-0003-4749-7950
Qiang FuTianjin Key Laboratory for Control Theory & Application in Complicated Systems and Tianjin International Joint Research and Development Center, Tianjin University of Technology, Tianjin 300380, China.
Songyuan ZhangState Key Laboratory of Robotics and System, Harbin Institute of Technology, Harbin 150001, China.ORCID 0000-0001-9837-098X
Chunliu FanIntelligent Robot Laboratory, Tianjin University of Technology, Tianjin 300380, China.
Xi ZhangIntelligent Robot Laboratory, Tianjin University of Technology, Tianjin 300380, China.
Jian GuoTianjin Key Laboratory for Control Theory & Application in Complicated Systems and Tianjin International Joint Research and Development Center, Tianjin University of Technology, Tianjin 300380, China.
Shuxiang GuoDepartment of Intelligent Mechanical Systems Engineering, Kagawa University, Takamatsu 761-0396, Japan.

Funding

Innovative Cooperation Project of Tianjin Scientific and Technological Support 18PTZWHZ00090Natural Science Foundation of Tianjin 18JCYBJC43200Tianjin Key Laboratory for Control Theory and Application in Complicated Systems TJKL-CTACS-201903
6 · The paper itself

Abstract

Given that the current microrobot cannot achieve fixed-point and quantitative drug application in the gastrointestinal (GI) tract, a targeted drug delivery microrobot is proposed, and its principle and characteristics are studied. Through the control of an external magnetic field, it can actively move to the affected area to realize the targeted drug delivery function. The microrobot has a cam structure connected with a radially magnetized permanent magnet, which can realize two movement modes: movement and targeted drug delivery. Firstly, the magnetic actuated capsule microrobotic system (MACMS) is analyzed. Secondly, the dynamic model and quantitative drug delivery model of the targeted drug delivery microrobot driven by the spiral jet structure are established, and the motion characteristics of the targeted drug delivery microrobot are simulated and analyzed by the method of Computational Fluid Dynamics (CFD). Finally, the whole process of the targeted drug delivery task of the microrobot is simulated. The results show that the targeted drug delivery microrobot can realize basic movements such as forward, backward, fixed-point parking and drug delivery through external magnetic field control, which lays the foundation for gastrointestinal diagnosis and treatment.

Indexed as

cam structureComputational Fluid Dynamics (CFD)magnetic actuated capsule microrobotic system (MACMS)targeted drug delivery microrobot

Identifiers

PMID34683261
PMCPMC8541632

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.