Evidence map›Paper›PMID 34683202›Full record

ArticleMicromachines2021

A Portable Device for LAMP Based Detection of SARS-CoV-2.

Kamalalayam Rajan Sreejith, Muhammad Umer, Larissa Dirr, Benjamin Bailly, Patrice Guillon, Mark von Itzstein, Narshone Soda, Surasak Kasetsirikul, Muhammad J A Shiddiky, Nam-Trung Nguyen

Open access · goldAbstract read
In one paragraph

Article in Micromachines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Article
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  9. A portable system for economical nucleic acid amplification testing.Frontiers in bioengineering and biotechnology · 2023
    Article
  10. Review
  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Kamalalayam Rajan SreejithQueensland Micro- and Nanotechnology Centre, Griffith University, 170 Kessels Road, Nathan, QLD 4111, Australia.
Muhammad UmerQueensland Micro- and Nanotechnology Centre, Griffith University, 170 Kessels Road, Nathan, QLD 4111, Australia.ORCID 0000-0001-9983-0087
Larissa DirrInstitute for Glycomics, Gold Coast Campus, Griffith University, 1 Parklands Drive, Southport, QLD 4222, Australia.
Benjamin BaillyInstitute for Glycomics, Gold Coast Campus, Griffith University, 1 Parklands Drive, Southport, QLD 4222, Australia.ORCID 0000-0003-0782-2325
Patrice GuillonInstitute for Glycomics, Gold Coast Campus, Griffith University, 1 Parklands Drive, Southport, QLD 4222, Australia.ORCID 0000-0002-9639-183X
Mark von ItzsteinInstitute for Glycomics, Gold Coast Campus, Griffith University, 1 Parklands Drive, Southport, QLD 4222, Australia.ORCID 0000-0001-6302-7524
Narshone SodaQueensland Micro- and Nanotechnology Centre, Griffith University, 170 Kessels Road, Nathan, QLD 4111, Australia.ORCID 0000-0002-1921-7176
Surasak KasetsirikulQueensland Micro- and Nanotechnology Centre, Griffith University, 170 Kessels Road, Nathan, QLD 4111, Australia.
Muhammad J A ShiddikyQueensland Micro- and Nanotechnology Centre, Griffith University, 170 Kessels Road, Nathan, QLD 4111, Australia.
Nam-Trung NguyenQueensland Micro- and Nanotechnology Centre, Griffith University, 170 Kessels Road, Nathan, QLD 4111, Australia.ORCID 0000-0003-3626-5361
Griffith University · AU

Funding

Australian Research Council DP180100055
6 · The paper itself

Abstract

This paper reports the design, development, and testing of a novel, yet simple and low-cost portable device for the rapid detection of SARS-CoV-2. The device performs loop mediated isothermal amplification (LAMP) and provides visually distinguishable images of the fluorescence emitted from the samples. The device utilises an aluminium block embedded with a cartridge heater for isothermal heating of the sample and a single-board computer and camera for fluorescence detection. The device demonstrates promising results within 20 min using clinically relevant starting concentrations of the synthetic template. Time-to-signal data for this device are considerably lower compared to standard quantitative Polymerase Chain Reaction(qPCR) machine (~10-20 min vs. >38 min) for 1 × 10

Indexed as

loop-mediated isothermal amplificationportable devicesevere acute respiratory syndrome-coronavirus 2 (SARS-CoV-2)

Identifiers

PMID34683202
PMCPMC8538454
OpenAlexW3204472849

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.