Evidence map›Paper›PMID 34683136›Full record

ArticleJournal of personalized medicine2021

Exploring Implementation of Personal Breast Cancer Risk Assessments.

Maria A Sierra, Jack C W Wheeler, Lisa Devereux, Alison H Trainer, Louise Keogh

Open access · goldAbstract read
In one paragraph

Article in Journal of personalized medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 5 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 5 syntheses or guidelines pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Acceptability of risk stratification within population-based cancer screening from the perspective of the general public: A mixed-methods systematic review.Health expectations : an international journal of public participation in health care and health policy · 2023
    Pooled it
  5. Pooled it
  6. Article
  7. Article
  8. Article
  9. Cohort Profile: Lifepool.International journal of epidemiology · 2025
    Article
  10. Article
  11. Review
  12. Article
  13. Current oncology (Toronto, Ont.) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Maria A SierraMiller School of Medicine, University of Miami, Miami, FL 33136, USA.
Jack C W WheelerCentre for Health Equity, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, VIC 3000, Australia.ORCID 0000-0002-1046-6985
Lisa DevereuxResearch Division, Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, VIC 3000, Australia.
Alison H TrainerParkville Familial Cancer Centre, Melbourne, VIC 3000, Australia.ORCID 0000-0002-9847-3265
Louise KeoghCentre for Health Equity, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, VIC 3000, Australia.
The University of Melbourne · AUUniversity of Miami · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Personal Breast Cancer (BC) Risk Assessments (PBCRA) have potential to stratify women into clinically-actionable BC risk categories. As this could involve population-wide genomic testing, women's attitudes to PBCRA and views on acceptable implementation platforms must be considered to ensure optimal population participation. We explored these issues with 31 women with different BC risk profiles through semi-structured focus group discussions or interviews. Inductive thematic coding of transcripts was performed. Subsequently, women listed factors that would impact on their decision to participate. Participants' attitudes to PBCRA were positive. Identified themes included that PBCRA acceptance hinges on result actionability. Women value the ability to inform decision-making. Participants reported anxiety, stress, and genetic discrimination as potential barriers. The age at which PBCRA was offered, ease of access, and how results are returned held importance. Most women value the opportunity for PBCRA to inform increased surveillance, while highlighting hesitance to accept reduced surveillance as they find reassurance in regular screening. Women with

Indexed as

breast cancer riskimplementationpolygenic riskrisk-stratified breast screening

Identifiers

PMID34683136
PMCPMC8541275
OpenAlexW3203177976

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.