Evidence map›Paper›PMID 34683091›Full record

ReviewJournal of personalized medicine2021

Emerging Minimally Invasive Technologies for the Detection of Skin Cancer.

Joon Min Jung, Ji Young Cho, Woo Jin Lee, Sung Eun Chang, Mi Woo Lee, Chong Hyun Won

Open access · goldAbstract readReview
In one paragraph

Review in Journal of personalized medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
1.3field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. High-frequency ultrasound accuracy in preoperative cutaneous melanoma assessment: A meta-analysis.Journal of the European Academy of Dermatology and Venereology : JEADV · 2025
    Pooled it
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  14. Cutaneous Oncology: Strategies for Melanoma Prevention, Diagnosis, and Therapy.Cancer control : journal of the Moffitt Cancer Center
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Joon Min JungDepartment of Dermatology, Asan Medical Center, University of Ulsan College of Medicine, Seoul 05505, Korea.ORCID 0000-0003-3432-8306
Ji Young ChoDepartment of Medical Science, Asan Medical Institute of Convergence Science and Technology, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul 05505, Korea.
Woo Jin LeeDepartment of Dermatology, Asan Medical Center, University of Ulsan College of Medicine, Seoul 05505, Korea.
Sung Eun ChangDepartment of Dermatology, Asan Medical Center, University of Ulsan College of Medicine, Seoul 05505, Korea.
Mi Woo LeeDepartment of Dermatology, Asan Medical Center, University of Ulsan College of Medicine, Seoul 05505, Korea.
Chong Hyun WonDepartment of Dermatology, Asan Medical Center, University of Ulsan College of Medicine, Seoul 05505, Korea.
Ulsan College · KR

Funding

the Korea Medical Device Development Fund grant funded by the Korea government (the Min-istry of Science and ICT, the Ministry of Trade, Industry and Energy, the Ministry of Health & Welfare, the Ministry of Food and Drug Safety) NTIS, KMDF-RnD 1711137939the Korea Research-driven Hospitals Project funded by the Korea Health Industry Development Institute (KHIDI) H18C2383
6 · The paper itself

Abstract

With the increasing incidence of skin cancer, many noninvasive technologies to detect its presence have been developed. This review focuses on reflectance confocal microscopy (RCM), optical coherence tomography (OCT), high-frequency ultrasound (HFUS), electrical impedance spectroscopy (EIS), pigmented lesion assay (PLA), and Raman spectroscopy (RS) and discusses the basic principle, clinical applications, advantages, and disadvantages of each technology. RCM provides high cellular resolution and has high sensitivity and specificity for the diagnosis of skin cancer. OCT provides lower resolution than RCM, although its evaluable depth is deeper than that of RCM. RCM and OCT may be useful in reducing the number of unnecessary biopsies, evaluating the tumor margin, and monitoring treatment response. HFUS can be mainly used to delineate tumor depths or margins and monitor the treatment response. EIS provides high sensitivity but low specificity for the diagnosis of skin malignancies. PLA, which is based on the genetic information of lesions, is applicable for the detection of melanoma with high sensitivity and moderate-to-high specificity. RS showed high accuracy for the diagnosis of skin cancer, although more clinical studies are required. Advances in these technologies for the diagnosis of skin cancer can lead to the realization of optimized and individualized treatments.

Indexed as

basal cell carcinomaelectrical impedance spectroscopyhigh-frequency ultrasoundmelanomaoptical coherence tomographypigmented lesion assayRaman spectroscopyreflectance confocal microscopyskin cancersquamous cell carcinoma

Identifiers

PMID34683091
PMCPMC8538732
OpenAlexW3201700502

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.