Evidence map›Paper›PMID 34683018›Full record

ArticleHealthcare (Basel, Switzerland)2021

Left Ventricular Systolic Impairment after Pediatric Cardiac Surgery Assessed by STE Analysis.

Massimiliano Cantinotti, Pietro Marchese, Marco Scalese, Paola Medino, Vivek Jani, Eliana Franchi, Pak Vitali, Giuseppe Santoro, Cecilia Viacava, Nadia Assanta and 3 more

Open access · goldAbstract read
In one paragraph

Article in Healthcare (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Myocardial deformation in children post cardiac surgery, a cross-sectional prospective study.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2024
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 3 countries.

Massimiliano CantinottiFondazione G. Monasterio CNR-Regione Toscana, 54100 Massa, Italy.
Pietro MarcheseFondazione G. Monasterio CNR-Regione Toscana, 54100 Massa, Italy.ORCID 0000-0003-4801-608X
Marco ScaleseInstitute of Clinical Physiology, IFC, National Research Institute (CNR), 56121 Pisa, Italy.
Paola MedinoFondazione G. Monasterio CNR-Regione Toscana, 54100 Massa, Italy.
Vivek JaniThe Helen B. Taussig Heart Center, The Johns Hopkins Hospital and Johns Hopkins University, Baltimore, MD 21218, USA.ORCID 0000-0002-3811-4973
Eliana FranchiFondazione G. Monasterio CNR-Regione Toscana, 54100 Massa, Italy.
Pak VitaliFondazione G. Monasterio CNR-Regione Toscana, 54100 Massa, Italy.
Giuseppe SantoroFondazione G. Monasterio CNR-Regione Toscana, 54100 Massa, Italy.
Cecilia ViacavaFondazione G. Monasterio CNR-Regione Toscana, 54100 Massa, Italy.
Nadia AssantaFondazione G. Monasterio CNR-Regione Toscana, 54100 Massa, Italy.
Shelby KuttyThe Helen B. Taussig Heart Center, The Johns Hopkins Hospital and Johns Hopkins University, Baltimore, MD 21218, USA.
Martin KoestenbergerDepartment of Pediatrics, Division of Pediatric Cardiology, Medical University, 8036 Graz, Austria.ORCID 0000-0003-1766-7859
Raffaele GiordanoAdult and Pediatric Cardiac Surgery Unit, Department of Advanced Biomedical Sciences, University of Naples Federico II, 80138 Naples, Italy.
Fondazione Toscana Gabriele Monasterio · ITIstituto di Fisiologia Clinica · ITJohns Hopkins University · USMedical University of Graz · ATUniversity of Naples Federico II · ITUniversity of Pisa · IT

Funding

Medical Scientist Training ProgramT32GM136577 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI ANDREA L COX · 2020 to 2026
$13.4M
NIGMS NIH HHS T32 GM136577
6 · The paper itself

Abstract

backgroundSpeckle-tracking echocardiography (STE) has gained increasing value in the evaluation of congenital heart diseases (CHD); however, its use in pediatric cardiac surgery is limited.

aimTo evaluate left ventricular (LV) systolic impairment after biventricular pediatric cardiac surgery by STE strain (ε) analysis.

methodsWe prospectively enrolled 117 children undergoing cardiac surgery for CHD. Echocardiography was performed at four different times: pre-operatively, 12-36 h (Time 1), 3-5 days (Time 2), and 6-8 days (Time 3). Images were obtained in the 4-2-and 3 apical chamber's views to derive LV global and regional (basal/mid/apical) ε values.

resultsAt different postoperative times, we performed 320 examinations in 117 children (mean age: 2.4 ± 3.9, range: 0-16 years); 117 age-matched healthy children served as controls. All global, basal, and mid LVε values decreased after surgery; the lowest values being at Time 1 (

conclusionsSTE ε analysis revealed a significant LV systolic impairment after surgery with amelioration thereafter but incomplete normalization at discharge. Base-apex differences emerged with apical segments that, contrary to all the other regions, showed relative hypercontractility after surgery. The slower recovery of LVε values compared to LVEF suggests that STE ε analysis may be more accurate for the follow-up of mild LV post-surgical impairment.

Indexed as

cardiac surgerycongenital heart diseaseechocardiographyspeckle tracking echocardiography

Identifiers

PMID34683018
PMCPMC8544436
OpenAlexW3207232708

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.