Evidence map›Paper›PMID 34682918›Full record

ArticleJournal of clinical medicine2021

Recurrence of Gestational Diabetes Mellitus: To Assess Glucose Metabolism and Clinical Risk Factors at the Beginning of a Subsequent Pregnancy.

Grammata Kotzaeridi, Julia Blätter, Daniel Eppel, Ingo Rosicky, Veronica Falcone, Gabriela Adamczyk, Tina Linder, Gülen Yerlikaya-Schatten, Karen Weisshaupt, Wolfgang Henrich and 2 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 3 pooled it
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 3 syntheses or guidelines pooled it, 19 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 3 countries.

Grammata KotzaeridiDepartment of Obstetrics and Gynecology, Medical University of Vienna, 1090 Vienna, Austria.
Julia BlätterDepartment of Obstetrics and Gynecology, Medical University of Vienna, 1090 Vienna, Austria.
Daniel EppelDepartment of Obstetrics and Gynecology, Medical University of Vienna, 1090 Vienna, Austria.
Ingo RosickyDepartment of Obstetrics and Gynecology, Medical University of Vienna, 1090 Vienna, Austria.
Veronica FalconeDepartment of Obstetrics and Gynecology, Medical University of Vienna, 1090 Vienna, Austria.ORCID 0000-0002-2412-1822
Gabriela AdamczykDepartment of Obstetrics and Gynecology, Medical University of Vienna, 1090 Vienna, Austria.
Tina LinderDepartment of Obstetrics and Gynecology, Medical University of Vienna, 1090 Vienna, Austria.
Gülen Yerlikaya-SchattenDepartment of Obstetrics and Gynecology, Medical University of Vienna, 1090 Vienna, Austria.ORCID 0000-0002-9214-740X
Karen WeisshauptClinic of Obstetrics, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, 13353 Berlin, Germany.ORCID 0000-0003-0526-8594
Wolfgang HenrichClinic of Obstetrics, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, 13353 Berlin, Germany.
Andrea TuraMetabolic Unit, CNR Institute of Neuroscience, 35127 Padova, Italy.
Christian S GöblDepartment of Obstetrics and Gynecology, Medical University of Vienna, 1090 Vienna, Austria.
Medical University of Vienna · ATHumboldt-Universität zu Berlin · DENeuroscience Institute · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Women with a history of gestational diabetes mellitus (GDM) are at high risk of developing hyperglycemia in a subsequent pregnancy. This study aimed to assess parameters of glucose metabolism at the beginning of a subsequent pregnancy in women with a history of GDM. This prospective cohort study included 706 women who had at least one previous pregnancy (120 with prior GDM and 586 without GDM history). All study participants received a broad risk evaluation and laboratory testing at the beginning of a subsequent pregnancy and were followed up until delivery to assess GDM status, risk factors for GDM recurrence, and pregnancy outcomes. Women with a history of GDM exhibited lower insulin sensitivity and subtle impairments in β-cell function associated with subclinical hyperglycemia already at the beginning of a subsequent pregnancy compared to women without GDM history. This was associated with a markedly increased risk for the later development of GDM (OR: 6.59, 95% CI 4.34 to 10.09,

Indexed as

epidemiologyGDM recurrencegestational diabetes mellitushyperglycemiapregnancy

Identifiers

PMID34682918
PMCPMC8540668
OpenAlexW3207676440

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.