ReviewJournal of clinical medicine2021
The Role of Uric Acid in Acute and Chronic Coronary Syndromes.
Review in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05770323 (The Association Between Serum Uric Acid Level and Acute Coronary Syndrome in_hospital Outcomes), which is not on this map. Cited by 39 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Association Between Serum Uric Acid Level and Acute Coronary Syndrome in_hospital Outcomes
Who cites it
39 citing papers in PubMed, 55 citations in OpenAlex.
- Disentangling Uric Acid and Renal Pathways in SGLT2 Inhibitor Effects After Acute Myocardial Infarction: A Retrospective Mediation Analysis.Biomedicines · 2026Article
- Circulating Mitochondrial Open Reading Frame of the 12S Ribosomal RNA Type-c Is Higher in Acute Coronary Syndrome and Is a Prognostic Biomarker for Major Cardiac Events in Patients With Acute Myocardial Infarction: A Case-Control Study.Journal of the American Heart Association · 2025Article
- Association of exposure duration, modality, and polycythaemia with hyperuricaemia among han male immigrants at high altitudes: a cross-sectional study.Annals of medicine · 2025Article
- The influence of serum uric acid on risks of major adverse cardiovascular events in patients with acute coronary syndrome.BMC cardiovascular disorders · 2025Article
- Gender differences in the predictive value of serum uric acid for major adverse cardiovascular events in patients with acute coronary syndromes: a retrospective cohort study.BMC cardiovascular disorders · 2025Article
- A Patient Presenting with Joint Deformities and ST-Elevation Myocardial Infarction.Diagnostics (Basel, Switzerland) · 2025Article
- Effects of febuxostat on heart failure patients with asymptomatic hyperuricaemia: a retrospective cohort study.BMJ open · 2025Article
- A retrospective study of the association between serum uric acid and risk of coronary heart disease complicated with different types of chronic heart failure.European journal of medical research · 2025Article
- New Insights into Uric Acid Metabolism in the Pathophysiology of Ischaemic Heart Disease.European cardiology · 2025Review
- Prognostic role of the serum uric acid-to-serum creatinine ratio in patients with st-elevation myocardial infarction and multivessel coronary artery disease.Cardiology journal · 2025Article
- Relation between uric acid and stroke in aortic dissection.Journal of thoracic disease · 2024Article
- Hyperuricemia in Cardiac Rehabilitation Patients: Prevalence and Association with Functional Improvement and Left Ventricular Ejection Fraction.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2024Article
- Uric acid to albumin ratio as a novel predictor for coronary slow flow phenomenon in patients with chronic coronary syndrome and non-obstructive coronary arteries.BMC cardiovascular disorders · 2024Article
- Single photon emission computed tomography/computed tomography imaging of gouty arthritis: A new voice.Journal of translational internal medicine · 2024Article
- The association between serum uric acid / serum creatinine ratio and in-hospital outcomes in elderly patients with acute myocardial infarction.BMC cardiovascular disorders · 2024Article
- Ceramides and pro-inflammatory cytokines for the prediction of acute coronary syndrome: a multi-marker approach.BMC cardiovascular disorders · 2024Article
- Expert consensus for the diagnosis and treatment of patients with hyperuricemia and high cardiovascular risk: 2023 update.Cardiology journal · 2024Article
- Gender-specific association between blood cell parameters and hyperuricemia in high-altitude areas.Frontiers in public health · 2024Article
- Uric acid and evaluate the coronary vascular stenosis gensini score correlation research and in gender differences.BMC cardiovascular disorders · 2023Article
- Secondary Prevention and Extreme Cardiovascular Risk Evaluation (SEVERE-1), Focus on Prevalence and Associated Risk Factors: The Study Protocol.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2023Article
Corrections and comments
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Authors and funding
17 authors at 2 institutions in 1 country.
Funding
Abstract
Uric acid (UA) is the final product of the catabolism of endogenous and exogenous purine nucleotides. While its association with articular gout and kidney disease has been known for a long time, new data have demonstrated that UA is also related to cardiovascular (CV) diseases. UA has been identified as a significant determinant of many different outcomes, such as all-cause and CV mortality, and also of CV events (mainly Acute Coronary Syndromes (ACS) and even strokes). Furthermore, UA has been related to the development of Heart Failure, and to a higher mortality in decompensated patients, as well as to the onset of atrial fibrillation. After a brief introduction on the general role of UA in CV disorders, this review will be focused on UA's relationship with CV outcomes, as well as on the specific features of patients with ACS and Chronic Coronary Syndrome. Finally, two issues which remain open will be discussed: the first is about the identification of a CV UA cut-off value, while the second concerns the possibility that the pharmacological reduction of UA is able to lower the incidence of CV events.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.