Evidence map›Paper›PMID 34682739›Full record

ArticleInternational journal of environmental research and public health2021

Gender and Socioeconomic Inequality in the Prescription of Direct Oral Anticoagulants in Patients with Non-Valvular Atrial Fibrillation in Primary Care in Catalonia (Fantas-TIC Study).

Mª Rosa Dalmau Llorca, Carina Aguilar Martín, Noèlia Carrasco-Querol, Zojaina Hernández Rojas, Emma Forcadell Drago, Dolores Rodríguez Cumplido, Elisabet Castro Blanco, Josep Mª Pepió Vilaubí, Alessandra Queiroga Gonçalves, José Fernández-Sáez

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 22 citations in OpenAlex.

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  5. Quality of Oral Anticoagulation Control with Warfarin According to Sex: A Cross-Sectional Study.International journal of environmental research and public health · 2025
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  8. Social drivers in atrial fibrillation occurrence, screening, treatment, and outcomes: systematic-narrative hybrid review.European heart journal supplements : journal of the European Society of Cardiology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Mª Rosa Dalmau LlorcaEquip d'Atenció Primària Terres de l'Ebre, Institut Català de la Salut, 43500 Tortosa, Catalonia, Spain.ORCID 0000-0001-7537-5307
Carina Aguilar MartínPrimary Care Intervention Evaluation Research Group (GAVINA Research Group), IDIAPJGol Terres de l'Ebre, 43500 Tortosa, Catalonia, Spain.
Noèlia Carrasco-QuerolPrimary Care Intervention Evaluation Research Group (GAVINA Research Group), IDIAPJGol Terres de l'Ebre, 43500 Tortosa, Catalonia, Spain.ORCID 0000-0002-5876-7082
Zojaina Hernández RojasEquip d'Atenció Primària Terres de l'Ebre, Institut Català de la Salut, 43500 Tortosa, Catalonia, Spain.
Emma Forcadell DragoEquip d'Atenció Primària Terres de l'Ebre, Institut Català de la Salut, 43500 Tortosa, Catalonia, Spain.
Dolores Rodríguez CumplidoPrimary Care Intervention Evaluation Research Group (GAVINA Research Group), IDIAPJGol Terres de l'Ebre, 43500 Tortosa, Catalonia, Spain.ORCID 0000-0001-5588-7153
Elisabet Castro BlancoCampus Terres de l'Ebre, Universitat Rovira i Virgili, 43500 Tortosa, Catalonia, Spain.
Josep Mª Pepió VilaubíPrimary Care Intervention Evaluation Research Group (GAVINA Research Group), IDIAPJGol Terres de l'Ebre, 43500 Tortosa, Catalonia, Spain.
Alessandra Queiroga GonçalvesPrimary Care Intervention Evaluation Research Group (GAVINA Research Group), IDIAPJGol Terres de l'Ebre, 43500 Tortosa, Catalonia, Spain.ORCID 0000-0003-3272-6861
José Fernández-SáezCampus Terres de l'Ebre, Universitat Rovira i Virgili, 43500 Tortosa, Catalonia, Spain.ORCID 0000-0002-6717-7674
Institut Universitari d'Investigació en Atenció Primària Jordi Gol · ESInstitut Català de la Salut · ESBellvitge University Hospital · ESUniversitat Rovira i Virgili · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEvidence points to unequal access to direct oral anticoagulant (DOAC) therapy, to the detriment of the most socioeconomically disadvantaged patients in different geographic areas; however, few studies have focused on people with atrial fibrillation. This study aimed to assess gender-based and socioeconomic differences in the prescriptions of anticoagulants in people with non-valvular atrial fibrillation who attended Primary Care.

methodA cross-sectional study with real-world data from patients treated in Primary Care in Catalonia (Spain). Data were obtained from the SIDIAP database, covering 287 Primary Care centers in 2018. Results were presented as descriptive statistics and odds ratios estimated by multivariable logistic regression.

resultsA total of 60,978 patients on anticoagulants for non-valvular atrial fibrillation were identified: 41,430 (68%) were taking vitamin K antagonists and 19,548 (32%), DOACs. Women had higher odds of treatment with DOAC (adjusted odds ratio [ORadj] 1.12), while lower DOAC prescription rates affected patients from Primary Care centers located in high-deprivation urban centers (ORadj 0.58) and rural areas (ORadj 0.34).

conclusionsDOAC prescription patterns differ by population. Women are more likely to receive it than men, while people living in rural areas and deprived urban areas are less likely to receive this therapy. Following clinical management guidelines could help to minimize the inequality.

Indexed as

Atrial FibrillationStrokeAdministration, OralAnticoagulantsCross-Sectional StudiesFemaleHumansMalePrescriptionsPrimary Health CareSocioeconomic FactorsSpainAnticoagulantsatrial fibrillationdirect oral anticoagulantssex-related differencessocioeconomic inequalitiesvitamin K antagonists

Identifiers

PMID34682739
PMCPMC8535825
OpenAlexW3205689859

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.