Evidence map›Paper›PMID 34682567›Full record

ArticleInternational journal of environmental research and public health2021

Multi-Task Learning-Based Immunofluorescence Classification of Kidney Disease.

Sai Pan, Yibing Fu, Pu Chen, Jiaona Liu, Weicen Liu, Xiaofei Wang, Guangyan Cai, Zhong Yin, Jie Wu, Li Tang and 6 more

Abstract read
In one paragraph

Article in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Sai PanNational Clinical Research Center for Kidney Diseases, State Key Laboratory of Kidney Diseases, Institute of Nephrology of Chinese PLA, Department of Nephrology, General Hospital of Chinese PLA, Medical School of Chinese PLA, Beijing 100853, China.
Yibing FuSchool of Electronic and Information Engineering, Beihang University, Beijing 100191, China.
Pu ChenNational Clinical Research Center for Kidney Diseases, State Key Laboratory of Kidney Diseases, Institute of Nephrology of Chinese PLA, Department of Nephrology, General Hospital of Chinese PLA, Medical School of Chinese PLA, Beijing 100853, China.
Jiaona LiuNational Clinical Research Center for Kidney Diseases, State Key Laboratory of Kidney Diseases, Institute of Nephrology of Chinese PLA, Department of Nephrology, General Hospital of Chinese PLA, Medical School of Chinese PLA, Beijing 100853, China.
Weicen LiuNational Clinical Research Center for Kidney Diseases, State Key Laboratory of Kidney Diseases, Institute of Nephrology of Chinese PLA, Department of Nephrology, General Hospital of Chinese PLA, Medical School of Chinese PLA, Beijing 100853, China.
Xiaofei WangSchool of Electronic and Information Engineering, Beihang University, Beijing 100191, China.
Guangyan CaiNational Clinical Research Center for Kidney Diseases, State Key Laboratory of Kidney Diseases, Institute of Nephrology of Chinese PLA, Department of Nephrology, General Hospital of Chinese PLA, Medical School of Chinese PLA, Beijing 100853, China.
Zhong YinNational Clinical Research Center for Kidney Diseases, State Key Laboratory of Kidney Diseases, Institute of Nephrology of Chinese PLA, Department of Nephrology, General Hospital of Chinese PLA, Medical School of Chinese PLA, Beijing 100853, China.
Jie WuNational Clinical Research Center for Kidney Diseases, State Key Laboratory of Kidney Diseases, Institute of Nephrology of Chinese PLA, Department of Nephrology, General Hospital of Chinese PLA, Medical School of Chinese PLA, Beijing 100853, China.
Li TangNational Clinical Research Center for Kidney Diseases, State Key Laboratory of Kidney Diseases, Institute of Nephrology of Chinese PLA, Department of Nephrology, General Hospital of Chinese PLA, Medical School of Chinese PLA, Beijing 100853, China.
Yong WangNational Clinical Research Center for Kidney Diseases, State Key Laboratory of Kidney Diseases, Institute of Nephrology of Chinese PLA, Department of Nephrology, General Hospital of Chinese PLA, Medical School of Chinese PLA, Beijing 100853, China.
Shuwei DuanNational Clinical Research Center for Kidney Diseases, State Key Laboratory of Kidney Diseases, Institute of Nephrology of Chinese PLA, Department of Nephrology, General Hospital of Chinese PLA, Medical School of Chinese PLA, Beijing 100853, China.
Ning DaiSchool of Electronic and Information Engineering, Beihang University, Beijing 100191, China.
Lai JiangSchool of Electronic and Information Engineering, Beihang University, Beijing 100191, China.
Mai XuSchool of Electronic and Information Engineering, Beihang University, Beijing 100191, China.
Xiangmei ChenNational Clinical Research Center for Kidney Diseases, State Key Laboratory of Kidney Diseases, Institute of Nephrology of Chinese PLA, Department of Nephrology, General Hospital of Chinese PLA, Medical School of Chinese PLA, Beijing 100853, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic kidney disease is one of the most important causes of mortality worldwide, but a shortage of nephrology pathologists has led to delays or errors in its diagnosis and treatment. Immunofluorescence (IF) images of patients with IgA nephropathy (IgAN), membranous nephropathy (MN), diabetic nephropathy (DN), and lupus nephritis (LN) were obtained from the General Hospital of Chinese PLA. The data were divided into training and test data. To simulate the inaccurate focus of the fluorescence microscope, the Gaussian method was employed to blur the IF images. We proposed a novel multi-task learning (MTL) method for image quality assessment, de-blurring, and disease classification tasks. A total of 1608 patients' IF images were included-1289 in the training set and 319 in the test set. For non-blurred IF images, the classification accuracy of the test set was 0.97, with an AUC of 1.000. For blurred IF images, the proposed MTL method had a higher accuracy (0.94 vs. 0.93,

Indexed as

Renal Insufficiency, ChronicFluorescent Antibody TechniqueHumansLearningdeep learningimmunofluorescence imageskidneymulti-task learning

Identifiers

PMID34682567
PMCPMC8535636

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.