Evidence map›Paper›PMID 34682564›Full record

ReviewInternational journal of environmental research and public health2021

Bioprinting Technology in Skin, Heart, Pancreas and Cartilage Tissues: Progress and Challenges in Clinical Practice.

Eleonora Di Piazza, Elisabetta Pandolfi, Ilaria Cacciotti, Andrea Del Fattore, Alberto Eugenio Tozzi, Aurelio Secinaro, Luca Borro

Abstract readReview
In one paragraph

Review in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Eleonora Di PiazzaMultifactorial and Complex Disease Research Area, Preventive and Predictive Medicine Unit, Bambino Gesù Children's Hospital, IRCCS, 00146 Rome, Italy.
Elisabetta PandolfiMultifactorial and Complex Disease Research Area, Preventive and Predictive Medicine Unit, Bambino Gesù Children's Hospital, IRCCS, 00146 Rome, Italy.
Ilaria CacciottiEngineering Department, Niccolò Cusano University of Rome, INSTM RU, 00166 Rome, Italy.ORCID 0000-0002-3478-6510
Andrea Del FattoreGenetics and Rare Diseases Research Area, Bone Physiopathology Research Unit, Bambino Gesù Children's Hospital, IRCCS, 00146 Rome, Italy.ORCID 0000-0003-3848-412X
Alberto Eugenio TozziMultifactorial and Complex Disease Research Area, Preventive and Predictive Medicine Unit, Bambino Gesù Children's Hospital, IRCCS, 00146 Rome, Italy.ORCID 0000-0002-6884-984X
Aurelio SecinaroClinical Management and Technological Innovations Area, Department of Imaging, Bambino Gesù Children's Hospital, IRCCS, 00146 Rome, Italy.
Luca BorroClinical Management and Technological Innovations Area, Department of Imaging, Bambino Gesù Children's Hospital, IRCCS, 00146 Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bioprinting is an emerging additive manufacturing technique which shows an outstanding potential for shaping customized functional substitutes for tissue engineering. Its introduction into the clinical space in order to replace injured organs could ideally overcome the limitations faced with allografts. Presently, even though there have been years of prolific research in the field, there is a wide gap to bridge in order to bring bioprinting from "bench to bedside". This is due to the fact that bioprinted designs have not yet reached the complexity required for clinical use, nor have clear GMP (good manufacturing practices) rules or precise regulatory guidelines been established. This review provides an overview of some of the most recent and remarkable achievements for skin, heart, pancreas and cartilage bioprinting breakthroughs while highlighting the critical shortcomings for each tissue type which is keeping this technique from becoming widespread reality.

Indexed as

BioprintingCartilagePancreasTechnologyTissue Engineeringbioprintingcartilageclinical applicationsheartpancreasregenerative medicineskintissue engineering

Identifiers

PMID34682564
PMCPMC8535210

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.