Evidence map›Paper›PMID 34682522›Full record

Trial reportInternational journal of environmental research and public health2021

High Intensity Training Is an Effective Modality to Improve Long-Term Disability and Exercise Capacity in Chronic Nonspecific Low Back Pain: A Randomized Controlled Trial.

Jonas Verbrugghe, Dominique Hansen, Christophe Demoulin, Jeanine Verbunt, Nathalie Anne Roussel, Annick Timmermans

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07645859 (Comparison of High-Intensity Interval Training With Moderate-Intensity Connuous Training In Chronic Non-Specific Low Back Pain Patients), which is not on this map. Cited by 12 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 3 pooled it
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07645859 narecruitingnot on this mapstarted 2026, after this paper: background citation

Comparison of High-Intensity Interval Training With Moderate-Intensity Connuous Training In Chronic Non-Specific Low Back Pain Patients: Randomized Clinical Trial

TypeinterventionalSponsorDow University of Health SciencesRan2026 to 2026Enrolled80ConditionsChronic Non-Specific Low Back PainArmsBrisk walk and jog, Normal walk
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 3 syntheses or guidelines pooled it, 25 citations in OpenAlex.

  1. Advances in physiotherapy for chronic low-back pain: a level I systematic review.Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology · 2026
    Pooled it
  2. Pooled it
  3. Impact of education in patients undergoing physiotherapy for lower back pain: a level I systematic review and meta-analysis.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2025
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 2 countries.

Jonas VerbruggheREVAL-Rehabilitation Research Center, Faculty of Rehabilitation Sciences, Hasselt University, 3590 Diepenbeek, Belgium.ORCID 0000-0002-9990-7723
Dominique HansenREVAL-Rehabilitation Research Center, Faculty of Rehabilitation Sciences, Hasselt University, 3590 Diepenbeek, Belgium.
Christophe DemoulinDepartment of Sport and Rehabilitation Sciences, University of Liege, 4000 Liege, Belgium.
Jeanine VerbuntAdelante Centre of Expertise in Rehabilitation and Audiology, 6432CC Hoensbroek, The Netherlands.
Nathalie Anne RousselFaculty of Medicine and Health Sciences, University of Antwerp, 2000 Antwerp, Belgium.
Annick TimmermansREVAL-Rehabilitation Research Center, Faculty of Rehabilitation Sciences, Hasselt University, 3590 Diepenbeek, Belgium.ORCID 0000-0002-5461-947X
Hasselt University · BEJessa Hospital · BEMaastricht University · NLUniversity of Antwerp · BEUniversity of Liège · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Previous research indicates that high intensity training (HIT) is a more effective exercise modality, as opposed to moderate intensity training (MIT), to improve disability and physical performance in persons with chronic nonspecific low back pain (CNSLBP). However, it is unclear how well benefits are maintained after intervention cessation. This study aimed to evaluate the long-term effectiveness of HIT on disability, pain intensity, patient-specific functioning, exercise capacity, and trunk muscle strength, and to compare the long-term effectiveness of HIT with MIT in persons with CNSLBP. Persons with CNSLBP (

Indexed as

Chronic PainLow Back PainAdultExerciseExercise TherapyExercise ToleranceHumansMuscle Strengthchronic low back painexercise therapyhigh intensity training

Identifiers

PMID34682522
PMCPMC8535878
OpenAlexW3207218708

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.