Evidence map›Paper›PMID 34682436›Full record

ArticleInternational journal of environmental research and public health2021

Particulate Matter Exposure and Allergic Rhinitis: The Role of Plasmatic Extracellular Vesicles and Bacterial Nasal Microbiome.

Jacopo Mariani, Simona Iodice, Laura Cantone, Giulia Solazzo, Paolo Marraccini, Emanuele Conforti, Pallav A Bulsara, Maria Stella Lombardi, Robert P Howlin, Valentina Bollati and 1 more

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 3 pooled it
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 3 syntheses or guidelines pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Review
  5. Article
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 4 countries.

Jacopo MarianiEPIGET LAB, Department of Clinical Sciences and Community Health, University of Milan, 20122 Milan, Italy.ORCID 0000-0003-0584-7481
Simona IodiceEPIGET LAB, Department of Clinical Sciences and Community Health, University of Milan, 20122 Milan, Italy.ORCID 0000-0001-5594-8761
Laura CantoneEPIGET LAB, Department of Clinical Sciences and Community Health, University of Milan, 20122 Milan, Italy.ORCID 0000-0003-3660-129X
Giulia SolazzoEPIGET LAB, Department of Clinical Sciences and Community Health, University of Milan, 20122 Milan, Italy.ORCID 0000-0002-5370-7507
Paolo MarracciniDepartment of Preventive Medicine, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.
Emanuele ConfortiDepartment of Preventive Medicine, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.
Pallav A BulsaraGlaxoSmithKline Consumer Healthcare, Warren, NJ 07059, USA.
Maria Stella LombardiGlaxoSmithKline Consumer Healthcare, CH-1260 Nyon, Switzerland.ORCID 0000-0002-4105-7228
Robert P HowlinGlaxoSmithKline Consumer Healthcare, Weybridge KT13 0DE, UK.
Valentina BollatiEPIGET LAB, Department of Clinical Sciences and Community Health, University of Milan, 20122 Milan, Italy.ORCID 0000-0002-0370-9598
Luca FerrariEPIGET LAB, Department of Clinical Sciences and Community Health, University of Milan, 20122 Milan, Italy.ORCID 0000-0003-0103-2170
University of Milan · ITFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico · ITGlaxoSmithKline (Switzerland) · CHGlaxoSmithKline (United Kingdom) · GBGlaxoSmithKline (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Particulate matter (PM) exposure is linked to the worsening of respiratory conditions, including allergic rhinitis (AR), as it can trigger nasal and systemic inflammation. To unveil the underlying molecular mechanisms, we investigated the effects of PM exposure on the release of plasmatic extracellular vesicles (EV) and on the complex cross-talk between the host and the nasal microbiome. To this aim, we evaluated the effects of PM

Indexed as

Extracellular VesiclesMicrobiotaRhinitis, AllergicBacteriaHumansParticulate MatterParticulate Matterallergic rhinitisbacterial nasal microbiomeextracellular vesiclesparticulate matter exposure

Identifiers

PMID34682436
PMCPMC8535327
OpenAlexW3206920575

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.