Evidence map›Paper›PMID 34682348›Full record

Observational studyInternational journal of environmental research and public health2021

Effects of Breastfeeding on Endometriosis-Related Pain: A Prospective Observational Study.

Romana Prosperi Porta, Chiara Sangiuliano, Alessandra Cavalli, Laila Cristine Hirose Marques Pereira, Luisa Masciullo, Ilaria Piacenti, Sara Scaramuzzino, Maria Federica Viscardi, Maria Grazia Porpora

Abstract readObservational Study
In one paragraph

Observational study in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Romana Prosperi PortaIl Melograno, Maternity and Childbirth Empowerment Centres, 00179 Rome, Italy.
Chiara SangiulianoDepartment of Maternal and Child Health and Urological Sciences, Sapienza University of Rome, 00161 Rome, Italy.
Alessandra CavalliDepartment of Maternal and Child Health and Urological Sciences, Sapienza University of Rome, 00161 Rome, Italy.
Laila Cristine Hirose Marques PereiraDepartment of Maternal and Child Health and Urological Sciences, Sapienza University of Rome, 00161 Rome, Italy.
Luisa MasciulloDepartment of Maternal and Child Health and Urological Sciences, Sapienza University of Rome, 00161 Rome, Italy.
Ilaria PiacentiDepartment of Obstetrics and Gynecology, Santa Maria Della Stella Hospital, 05018 Orvieto, Italy.
Sara ScaramuzzinoDepartment of Maternal and Child Health and Urological Sciences, Sapienza University of Rome, 00161 Rome, Italy.
Maria Federica ViscardiDepartment of Maternal and Child Health and Urological Sciences, Sapienza University of Rome, 00161 Rome, Italy.ORCID 0000-0003-0979-8832
Maria Grazia PorporaDepartment of Maternal and Child Health and Urological Sciences, Sapienza University of Rome, 00161 Rome, Italy.ORCID 0000-0001-5556-3933

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endometriosis is a gynecological estrogen-dependent disease whose commonest pain symptoms are dysmenorrhea, dyspareunia, and acyclic chronic pelvic pain (CPP). Hormonal changes occurring during breastfeeding seem to reduce pain and disease recurrence. The aim of this observational prospective study was to assess the effect of breastfeeding on pain and endometriotic lesions in patients with endometriosis and to evaluate a possible correlation between the duration of breastfeeding, postpartum amenorrhea, and pain. Out of 156 pregnant women with endometriosis enrolled, 123 who breastfed were included in the study and were monitored for 2 years after delivery; 96/123 exclusively breastfed for at least 1 month. Mode of delivery, type and duration of breastfeeding, intensity of pain symptoms, and lesion size before pregnancy and during the 24-month follow-up were analyzed. All patients experienced a significant reduction in dysmenorrhea proportional to the duration of breastfeeding. CPP was significantly reduced only in women who exclusively breastfed. No significant improvement in dyspareunia was observed. Ovarian endometriomas were significantly reduced. Therefore, breastfeeding, particularly if exclusive, may cause improvement in dysmenorrhea and CPP proportional to the duration of breastfeeding, as well as a reduction in the size of ovarian endometriomas.

Indexed as

EndometriosisBreast FeedingDysmenorrheaFemaleHumansPelvic PainPregnancyProspective Studiesacyclic chronic pelvic painbreastfeedingdysmenorrheaendometriosisexclusive breastfeedingpostpartum amenorrhea

Identifiers

PMID34682348
PMCPMC8535640

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.